Preparation of spirocyclic oxindoles by cyclisation of an oxime to a nitrone and dipolar cycloaddition
Beth L. Ritchie, Alexandra Longcake and Iain Coldham
Beilstein J. Org. Chem. 2025, 21, 1890–1896.
https://doi.org/10.3762/bjoc.21.146
Chemical Information
Calculated using the Chemistry Development Kit 2.12
| Molecular Formula | C18H20N2O6 |
| Molecular Weight | 360.36 g/mol |
| Exact Mass | 360.1321 Da |
| InChI |
InChI=1S/C18H20N2O6/c1-19-11-7-5-4-6-10(11)18(17(19)23)8-12-13(15(21)24-2)14(16(22)25-3)26-20(12)9-18/h4-7,12-14H,8-9H2,1-3H3/t12?,13-,14-,18?/m0/s1
|
| InChIKey |
LUQXUXXMPNTAOS-HPGRBHQUSA-N
|
| SMILES |
CN1C2=C(C=CC=C2)C3(CC4[C@@H]([C@@H](C(=O)OC)ON4C3)C(=O)OC)C1=O
|
| Number of Atoms | 46 |
| Number of H-Bond Acceptors | 6 |
| Number of H-Bond Donors | 0 |
| Atoms in the Largest π-System | 9 |
| XLogP | -0.6 |
