From discovery to production: Scale-out of continuous flow meso reactors

Peter Styring and Ana I. R. Parracho
Beilstein J. Org. Chem. 2009, 5, No. 29. https://doi.org/10.3762/bjoc.5.29

Cite the Following Article

From discovery to production: Scale-out of continuous flow meso reactors
Peter Styring and Ana I. R. Parracho
Beilstein J. Org. Chem. 2009, 5, No. 29. https://doi.org/10.3762/bjoc.5.29

How to Cite

Styring, P.; Parracho, A. I. R. Beilstein J. Org. Chem. 2009, 5, No. 29. doi:10.3762/bjoc.5.29

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Polterauer, D.; Roberge, D. M.; Hanselmann, P.; Littich, R.; Hone, C. A.; Kappe, C. O. A continuous flow investigation of sulfonyl chloride synthesis using N-chloroamides: optimization, kinetics and mechanism. Reaction Chemistry & Engineering 2022, 7, 2582–2592. doi:10.1039/d2re00280a
  • Beckers, O.; Smeets, S.; Lutsen, L.; Maes, W. Perspective on the application of continuous flow chemistry for polymer-based organic electronics. Journal of Materials Chemistry C 2022, 10, 1606–1616. doi:10.1039/d1tc04635g
  • Hone, C. A.; Kappe, C. O. Towards the Standardization of Flow Chemistry Protocols for Organic Reactions. Chemistry–Methods 2021, 1, 454–467. doi:10.1002/cmtd.202100059
  • Bálint, E.; Tajti, Á.; Keglevich, G. Application of the Microwave Technique in Continuous Flow Processing of Organophosphorus Chemical Reactions. Materials (Basel, Switzerland) 2019, 12, 788. doi:10.3390/ma12050788
  • Biao, W.; Wang, Y.; Jiang, Y.; Chu, M.-M.; Qi, S.-S.; Ju, W.-Z.; Xu, D.-Q. Asymmetric fluorination of indanone-2-carboxylates using a polystyrene-supported diphenylamine-linked bis(oxazoline) complex. Organic & biomolecular chemistry 2018, 16, 7702–7710. doi:10.1039/c8ob01943f
  • Tamborini, L.; Fernandes, P.; Paradisi, F.; Molinari, F. Flow Bioreactors as Complementary Tools for Biocatalytic Process Intensification. Trends in biotechnology 2017, 36, 73–88. doi:10.1016/j.tibtech.2017.09.005
  • Pirotte, G.; Agarkar, S.; Xu, B.; Zhang, J.; Lutsen, L.; Vanderzande, D.; Yan, H.; Pollet, P.; Reynolds, J. R.; Maes, W.; Marder, S. R. Molecular weight tuning of low bandgap polymers by continuous flow chemistry: increasing the applicability of PffBT4T for organic photovoltaics. Journal of Materials Chemistry A 2017, 5, 18166–18175. doi:10.1039/c7ta05627c
  • Degennaro, L.; Carlucci, C.; De Angelis, S.; Luisi, R. Flow technology for organometallic-mediated synthesis. Journal of Flow Chemistry 2016, 6, 136–166. doi:10.1556/1846.2016.00014
  • Linares, N.; Moreno-Marrodan, C.; Barbaro, P. PdNP@Titanate Nanotubes as Effective Catalyst for Continuous-Flow Partial Hydrogenation Reactions. ChemCatChem 2016, 8, 1001–1011. doi:10.1002/cctc.201501126
  • Güveli, Ş.; Cinar, S. A.; Karahan, O.; Aviyente, V.; Ülküseven, B. Nickel(II)–PPh3 Complexes of S,N‐Substituted Thiosemicarbazones – Structure, DFT Study, and Catalytic Efficiency. European Journal of Inorganic Chemistry 2016, 2016, 538–544. doi:10.1002/ejic.201501227
  • Gürsel, I. V.; Kurt, S. K.; Aalders, J.; Wang, Q. Q.; Noël, T.; Nigam, K. D.; Kockmann, N.; Hessel, V. Utilization of milli-scale coiled flow inverter in combination with phase separator for continuous flow liquid-liquid extraction processes. Chemical Engineering Journal 2016, 283, 855–868. doi:10.1016/j.cej.2015.08.028
  • Nagaki, A.; Yoshida, J.-i. Preparation and Use of Organolithium and Organomagnesium Species in Flow. Organometallic Flow Chemistry; Springer International Publishing, 2015; pp 137–175. doi:10.1007/3418_2015_154
  • Mitic, A.; Gernaey, K. V. Process Intensification Tools in the Small‐Scale Pharmaceutical Manufacturing of Small Molecules. Chemical Engineering & Technology 2015, 38, 1699–1712. doi:10.1002/ceat.201400765
  • Egle, B.; de Muñoz, J. M.; Alonso, N.; De Borggraeve, W. M.; de la Hoz, A.; Díaz-Ortiz, A.; Alcázar, J. First Example of Alkyl-Aryl Negishi Cross-Coupling in Flow: Mild, Efficient and Clean Introduction of Functionalized Alkyl Groups. Journal of Flow Chemistry 2015, 4, 22–25. doi:10.1556/jfc-d-13-00009
  • Ager, D. J. ACS Symposium Series - Managing Hazardous Reactions and Compounds in Process Chemistry. ACS Symposium Series; American Chemical Society, 2014; pp 285–351. doi:10.1021/bk-2014-1181.ch012
  • Mitic, A.
  • Cantillo, D.; Kappe, C. O. Immobilized Transition Metals as Catalysts for Cross‐Couplings in Continuous Flow—A Critical Assessment of the Reaction Mechanism and Metal Leaching. ChemCatChem 2014, 6, 3286–3305. doi:10.1002/cctc.201402483
  • Manvar, A.; Shah, A. Continuous Flow and Microwave‐Assisted Vorbrüggen Glycosylations: Historical Perspective to High‐Throughput Strategies. Asian Journal of Organic Chemistry 2014, 3, 1134–1149. doi:10.1002/ajoc.201402119
  • Eliasen, A. M.; Thedford, R. P.; Claussen, K. R.; Yuan, C.; Siegel, D. A Protocol To Generate Phthaloyl Peroxide in Flow for the Hydroxylation of Arenes. Organic letters 2014, 16, 3628–3631. doi:10.1021/ol501497y
  • Nightingale, A. M.; Bannock, J. H.; Krishnadasan, S. H.; O'Mahony, F. T. F.; Haque, S. A.; Sloan, J.; Drury, C. J.; McIntyre, R.; deMello, J. C. Large-scale synthesis of nanocrystals in a multichannel droplet reactor. Journal of Materials Chemistry A 2013, 1, 4067–4076. doi:10.1039/c3ta10458c
Other Beilstein-Institut Open Science Activities