The C–F bond as a conformational tool in organic and biological chemistry

Scholarly Works

• Kaźmierczak, M.; Siodła, T.; Bilska‐Markowska, M. Regioselective Addition of Organolithium Reagents to Fluorinated Proline Amides: Insights from Experiment and Theory. ChemistrySelect 2025, 10. doi:10.1002/slct.202505278
• Freitas, M. P. Difluorinated Cyclohexanes: Energetics and Intra- and Intermolecular Interactions. Chemphyschem : a European journal of chemical physics and physical chemistry 2025, e202500648. doi:10.1002/cphc.202500648
• Haskologlu, I. C.; Erdag, E.; Uludag, O. Can Piperazine-Bearing Fluoro-Benzoxazolone Derivatives Be a Chronotherapeutic Solution for Pain Management?. Chronobiology in Medicine 2025, 7, 154–161. doi:10.33069/cim.2025.0044
• Dai, X.; Ye, H.-M.; Huang, G.; Li, G. Structure-Tunable Fluorinated Polyester Electrolytes with Enhanced Interfacial Stability for Recyclable Solid-State Lithium Metal Batteries. Advanced materials (Deerfield Beach, Fla.) 2025, e11556. doi:10.1002/adma.202511556
• Rozatian, N.; Roesner, S. Fluorine-containing macrocyclic peptides and peptidomimetics. Organic Chemistry Frontiers 2025, 12, 4871–4895. doi:10.1039/d5qo00219b
• Luo, H.; Cai, X.; Li, Z.; Hu, J.; Wu, T. Palladium-Catalyzed Addition of Allyl Fluorides to Gem-Difluoroolefins: Reorganization of C–F Bonds. ACS Catalysis 2025, 15, 12148–12156. doi:10.1021/acscatal.5c01996
• Khan, M. F. Recent Progress and Challenges in Microbial Defluorination and Degradation for Sustainable Remediation of Fluorinated Xenobiotics. Processes 2025, 13, 2017. doi:10.3390/pr13072017
• Lazare, J.; Tebes-Stevens, C.; Weber, E. J.; Shields, L. K. pKa Data-Driven Insights into Multiple Linear Regression Hydrolysis QSARs: Applicability to Perfluorinated Alkyl Esters. Environmental science & technology 2025, 59, 11745–11755. doi:10.1021/acs.est.4c11596
• Lai, E. Y.; Ackermann, L.; Johansson, M. J. A unified approach to meta-selective methylation, mono-, di- and trifluoromethylation of arenes. Chemical science 2025, 16, 8478–8486. doi:10.1039/d5sc01367d
• Lyu, Y.; Pünner, F.; Akakabe, M.; Sohtome, Y.; Sodeoka, M. Factors Controlling Diastereoselectivity and Reactivity in the Catalytic Aerobic Carbooxygenation of (E)-2-Fluoro-3-aryl-allyl Nitroacetates. Chemistry, an Asian journal 2025, 20, e202500336. doi:10.1002/asia.202500336
• Lobitz, A.; Steuber, A.; Jia, S.; Guo, L. Harnessing Fluorine Chemistry: Strategies for Per- and Polyfluoroalkyl Substances Removal and Enrichment. ChemPlusChem 2025, 90, e202400784. doi:10.1002/cplu.202400784
• Goel, N.; Kumari, P.; Gunjan; Phillips, A.; Bhagat, S. Recent Advances in Fluorination Reactions via De-Carboxylative and De-Oxygenative Strategies: A Perspective. Chemical record (New York, N.Y.) 2025, 25, e202500068. doi:10.1002/tcr.202500068
• Krafft, M. P. From fluorine's position in the periodic table to PFAS environmental issues. Comptes Rendus. Chimie 2025, 28, 423–438. doi:10.5802/crchim.391
• Luo, Z.; Qiu, H.; Peng, X.; Tan, Q.; Chen, B.; Gu, Q.; Liu, H.; Zhou, H. Development of potent inhibitors targeting bacterial prolyl-tRNA synthetase through fluorine scanning-directed activity tuning. European journal of medicinal chemistry 2025, 291, 117647. doi:10.1016/j.ejmech.2025.117647
• Mirabi, B.; Lautens, M.; Baik, M.-H. The rhodium riddle: computational insights into competitive β-hydride vs. β-fluoride elimination. Catalysis Science & Technology 2025, 15, 2482–2492. doi:10.1039/d4cy01495b
• Hooker, L. V.; Bandar, J. S. Capturing Unstable Carbanionic Intermediates via Halogen Transfer: Base‐Promoted Oxidative Coupling Reactions of α,α‐Difluoromethylarenes. Angewandte Chemie 2025, 137. doi:10.1002/ange.202502894
• Hooker, L. V.; Bandar, J. S. Capturing Unstable Carbanionic Intermediates via Halogen Transfer: Base-Promoted Oxidative Coupling Reactions of α,α-Difluoromethylarenes. Angewandte Chemie (International ed. in English) 2025, 64, e202502894. doi:10.1002/anie.202502894
• Ryan, P.; Iftikhar, R.; Hunter, L. Origami with small molecules: exploiting the C-F bond as a conformational tool. Beilstein journal of organic chemistry 2025, 21, 680–716. doi:10.3762/bjoc.21.54
• Do, T.; Kim, G. H.; Rios, R.; Yang, J. W. Recent advances in organocatalytic enantioselective syntheses of β-fluoroamine compounds. Molecular Catalysis 2025, 576, 114944. doi:10.1016/j.mcat.2025.114944
• Sıcak, Y.; Başaran, E.; Türkmenoğlu, B.; Öztürk, M. Synthesis of newly designed hydrazones, in vitro and in silico studies, and structure-activity relationship. Journal of Molecular Structure 2025, 1322, 140417. doi:10.1016/j.molstruc.2024.140417

Explore citations to this article at