Cite the Following Article
An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles
Marcus Baumann and Ian R. Baxendale
Beilstein J. Org. Chem. 2013, 9, 2265–2319.
https://doi.org/10.3762/bjoc.9.265
How to Cite
Baumann, M.; Baxendale, I. R. Beilstein J. Org. Chem. 2013, 9, 2265–2319. doi:10.3762/bjoc.9.265
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Tian, D.; He, Y.-P.; Yang, L.-S.; Li, Z.-C.; Wu, H. Switchable skeletal editing of quinolines enabled by cyclizative sequential rearrangements. Nature chemistry 2025. doi:10.1038/s41557-025-01793-0
- Presnukhina, S. I.; Baykova, S. O.; Chukanova, E. A.; Metalnikova, N. M.; Baykov, S. V.; Soldatova, N. S.; Postnikov, P. S.; Boyarskiy, V. P. Copper-catalyzed N-arylation of 1,2,4-oxadiazin-5(6H)-ones by diaryliodonium salts. Organic & biomolecular chemistry 2025. doi:10.1039/d5ob00204d
- Sajjadi, A.; Mayani, S. V.; Ballal, S.; Al-Hasnaawei, S.; Singh, A.; Chennakesavulu, K.; Joshi, K. K. Ultrasound-enhanced A3 coupling: Ferrocene-infused ionic liquid on silica nanospheres for efficient Quinoline derivatives synthesis. Tetrahedron 2025, 134633. doi:10.1016/j.tet.2025.134633
- Nguyen, H. T.; Nguyen, T. T.; Chau Doan, V. T.; Nguyen, T. H.; Tran, M. H. Recent advances in metal-free catalysts for the synthesis of N-heterocyclic frameworks focusing on 5- and 6-membered rings: a review. RSC advances 2025, 15, 9676–9755. doi:10.1039/d5ra00962f
- Oyamada, Y.; Ishikawa, K.; Takehara, T.; Suzuki, T.; Nakamura, S. Enantioselective modular synthesis of α-aryl-α-heteroaryl aminonitriles with parts per million organocatalyst loading: mechanistic investigation for stereochemical origins. Organic Chemistry Frontiers 2025, 12, 2382–2392. doi:10.1039/d4qo02362e
- Huang, F.; Li, M.; Jiang, Q.; Huang, Q.; Zhang, S.; Wei, H.; Li, Y.; Yu, Y.; Zhao, L.; Baell, J. Platform of Oxidative Transformation of α-Methyl Secondary Enaminones toward Tetrahydropyridines. The Journal of organic chemistry 2025, 90, 4186–4201. doi:10.1021/acs.joc.4c02687
- Liao, H.; Dong, J.; Zhou, X.; Jiang, Q.; Lv, Z.; Lei, F.; Xue, D. Silver-mediated formal [4π + 2σ] cycloaddition reactions of bicyclobutanes with nitrile imines: access to 2,3-diazobicyclo[3.1.1]heptenes. Chemical science 2025, 16, 4654–4660. doi:10.1039/d4sc08280j
- Lei, Z.-J.; Ma, Y.-J.; Fan, Q.-Q.; Wu, Z.-X.; Zheng, Y.-Y.; Sun, G.; Xi, Z.-W.; Shen, C.; Shen, Y.-M. Visible-Light-Mediated Three-Component Alkene 1,2-Alkylpyridylation Reaction Using Alkylboronic Acids as Radical Precursors for the Synthesis of 4-Alkylpyridines. The Journal of organic chemistry 2025, 90, 3563–3569. doi:10.1021/acs.joc.4c02600
- Yang, M.; Wang, M.; Zhang, H.; Qin, S.; Zaman, M.; Luo, J.; Zhan, S.; Wang, X.; Zhang, C.; Wang, S.; Gao, H.; Zhou, Z.; Hashmi, A. S. K.; Yi, W.; Zeng, Z. Unlocking redox-active reactivity of dearomatized pyridines with photochemistry toward meta-C–H functionalization of pyridines. Chem Catalysis 2025, 101326. doi:10.1016/j.checat.2025.101326
- Yedase, G. S.; Murgeshan, R.; Yatham, V. R. Minisci C-H Alkylation of Heterocycles with Unactivated Alkyl Iodides Enabled by Visible Light Photocatalysis. The Journal of organic chemistry 2025, 90, 3412–3419. doi:10.1021/acs.joc.4c03151
- Khan, A.; Dawar, P.; De, S. Thiourea compounds as multifaceted bioactive agents in medicinal chemistry. Bioorganic chemistry 2025, 158, 108319. doi:10.1016/j.bioorg.2025.108319
- Li, W.; Chen, Y.; Yuan, R.; Jia, X.; Yao, Y.; Zhang, L. Water‐Stable 2‐Pyridylboron Reagents: Pd‐Catalyzed 2‐Pyridylation Reaction of Aryl Halides. Angewandte Chemie 2025. doi:10.1002/ange.202500315
- Li, W.; Chen, Y.; Yuan, R.; Jia, X.; Yao, Y.; Zhang, L. Water-Stable 2-Pyridylboron Reagents: Pd-Catalyzed 2-Pyridylation Reaction of Aryl Halides. Angewandte Chemie (International ed. in English) 2025, e202500315. doi:10.1002/anie.202500315
- Xu, X.; Wang, J.; Chen, S.; Chen, X.; Chen, J.; Liu, Q.; Wang, Z.; Tian, M.; Sun, K. Visible Light‐Promoted Cascade Sulfonylation‐Cyclization‐Aromatization of Tertiary Enamides to Access Multi‐Substituted Pyridines and 1,2‐Dihydropyridines. Advanced Synthesis & Catalysis 2025. doi:10.1002/adsc.202401516
- Ranganathan, K.; Subramaniyan, M.; Kamatchi, T.; Shreedevi, S. Research design, evaluation, and in vitro assessment of N'-(thiophene-2-carbonyl) pyridine-4-carbohydrazide as a biological agent. Journal of Molecular Structure 2025, 1322, 140310. doi:10.1016/j.molstruc.2024.140310
- Chen, X.; Chen, S.; Wang, J.; Chen, J.; Tian, M.; Li, J.; Liu, Q.; Wang, Z.-L.; Xu, X.-M. Divergent Synthesis of Polysubstituted 1,2-Dihydropyridines and Pyridines through Manganese-Mediated Radical Cascade Cyclization of Tertiary Enamides. The Journal of organic chemistry 2025, 90, 2062–2076. doi:10.1021/acs.joc.4c02910
- Ravi, S.; Maddocks, C. J.; Fairlamb, I. J. S.; Unsworth, W. P.; Clarke, P. A. Asymmetric 'Clip-Cycle' synthesis of 3-spiropiperidines. Organic & biomolecular chemistry 2025, 23, 649–653. doi:10.1039/d4ob01608d
- Torabi, M.; Zolfigol, M. A.; Zarei, N.; Yarie, M.; Azizian, S. Engineering iodine decorated azo-bridged porous organic polymer: A brilliant catalyst for the preparation of 2,4,6-trisubstituted pyridines. Polymer 2025, 317, 127873. doi:10.1016/j.polymer.2024.127873
- Brahmachari, G. Visible light–driven organic synthesis under iridium (IrIII)-complex photocatalysis. Visible Light-Driven Organic Synthesis; Elsevier, 2025; pp 221–300. doi:10.1016/b978-0-323-95893-6.00004-9
- Wang, J.-P.; Liu, T.; Wu, Y.; Wang, P. Pd-Catalyzed Migratory 1,1-Cycloannulation Reaction of Alkenes. Journal of the American Chemical Society 2024, 147, 69–77. doi:10.1021/jacs.4c14153
Patents
- FLETCHER STEPHEN; MISHRA SOURABH. PROCESS. WO 2024213877 A1, Oct 17, 2024.