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Beilstein J. Org. Chem. 2026, 22, 1023–1032, doi:10.3762/bjoc.22.81
Graphical Abstract
Figure 1: Chemical structures of the known lichen natural products lecanoric acid (1), divaricatic acid (2), ...
Figure 2: ORTEP drawing of lecanoric acid (1).
Scheme 1: Reagents and conditions for the amidation optimisation study. i) Isopentylamine, rt, 1 h, yield 13%...
Figure 3: Chemical structures of the new semisynthetic amide analogues 6–13 generated from the purified liche...
Figure 4: Key COSY, HMBC and ROESY correlations for N-isopentyl-2,4-dihydroxy-6-methylbenzamide (6).