1 article(s) from Batalha, Pedro N
Structures of some bioactive 4-oxoquinoline-3-carboxamide derivatives 1–4 with different bioactive ...
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Structural modifications on the 4-oxo-1,4-dihydroquinoline-3-carboxamide scaffold.
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Synthetic route for the preparation of 1-ethyl-4-oxoquinoline-3-carboxamide 7.
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Reaction steps and main transition state leading to compound 7.
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Same scale partial 1H NMR spectra of compounds 5 and 7 (DMSO-d6, 500 MHz).
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1H,1H-COSY spectrum of derivative 7 (DMSO-d6, 500 MHz).
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Partial HMBC spectrum of derivative 7 (DMSO-d6, 500 MHz).
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Asymmetric unit of product 7.
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Deprotonation of 5 forming 8a and 8b, followed by reaction with bromoethane leading to products 7 a...
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Acid–base equilibria considered for the data displayed in Table 2.
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Charge dispersion due to resonance effects for both deprotonated species.
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Beilstein J. Org. Chem. 2019, 15, 388–400, doi:10.3762/bjoc.15.35
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