/ Home
/ SUBMISSION

/ The BJOC
/ Diamond Open Access
/ Journal Statistics
/ Editorial Board
/ Community
/ Call for papers

/ Latest Articles
/ Most accessed
/ Thematic issues
/ Featured collections
/ Volumes
/ Authors

/ E-Alerts

/ BlueSky
/ LINKEDIN
/ Mastodon
/ RSS FEED

Empty search

Article Type

Publication Date Range

Search Tips

This search combines search strings from the content search (i.e. "Full Text", "Author", "Title", "Abstract", or "Keywords") with "Article Type" and "Publication Date Range" using the AND operator.

Search Examples

aromatic	the word “aromatic”
aromatic aldehyde	the word “aromatic” OR “aldehyde”
+aromatic +aldehyde	both words “aromatic” AND “aldehyde”
+aromatic -aldehyde	the word “aromatic” but NOT “aldehyde”
“aromatic aldehyde”	the exact phrase “aromatic aldehyde”
benz*	words which begin with “benz”, such as “benzene” or “benzyl”
benz*yl	words that begin with “benz” and end with “yl”, such as “benzyl” or “benzoyl”
benzyl~	words that are close to the word “benzyl”, such as “benzoyl” (i.e., fuzzy search)

BROWSE
Latest Articles
Most accessed
thematic issues
Featured Collections
volumes
authors

BROWSE

Latest Articles Most Accessed Thematic Issues Featured Collections Volumes Authors

Author

1 article(s) from Berecz, Gábor

Synthesis of new tetra- and pentacyclic, methylenedioxy- and ethylenedioxy-substituted derivatives of the dibenzo[c,f][1,2]thiazepine ring system

Gábor Berecz,
András Dancsó,
Mária Tóthné Lauritz,
Loránd Kiss,
Gyula Simig and
Balázs Volk

Beilstein J. Org. Chem. 2025, 21, 2645–2656, doi:10.3762/bjoc.21.205

PDF

Graphical Abstract

Figure 1: Reported ring systems incorporating the dibenzo[c,f][1,2]thiazepine (1) skeleton.

Jump to Figure 1

Figure 2: Drugs exhibiting a 1,3-benzodioxole or 1,4-benzodioxane structural unit marketed or in development.

Jump to Figure 2

Scheme 1: Synthesis of tetracyclic key intermediates 6 and 7. Conditions: i) 1,3-benzodioxol-5-amine (n = 1)/...

Jump to Scheme 1

Scheme 2: Synthesis of tetracyclic compounds 20 and 21. Conditions: i) NaBH₄, DMF, EtOH, rt, 4.5 h/23 h, 95%/...

Jump to Scheme 2

Figure 3: X-ray structures of compounds 20e and 21g.

Jump to Figure 3

Scheme 3: Synthesis of tianeptine analogues 20b and 21b. Conditions: 20b: NaOH, EtOH/H₂O, rt, 25 h, 80%; 21b:...

Jump to Scheme 3

Scheme 4: Synthesis of tetracyclic ethers 23 and thioether 24. Conditions: i) ROH, MeCN, rt, 2–3 h, 38–84%; i...

Jump to Scheme 4

Figure 4: X-ray structure of compound 23a.

Jump to Figure 4

Scheme 5: Synthesis of pentacyclic compounds 25–27. Conditions: i) Py·HCl, 180 °C, 27 h, 51%; ii) Br(CH₂)₂Br,...

Jump to Scheme 5

Figure 5: X-ray structures of compounds 25, 26, and 27.

Jump to Figure 5

Scheme 6: Synthesis of tetracyclic compounds 38. Conditions: i) NaBH₄, DMF/EtOH, rt, 3 h, 89%; ii) SOCl₂, DCM...

Jump to Scheme 6

Scheme 7: Synthesis of tetracyclic compounds 45 and 46. Conditions: i) 2,3-dihydro-1,4-benzodioxin-5-amine, P...

Jump to Scheme 7

Scheme 8: Synthesis of tetracyclic compounds 54. Conditions: i) methyl anthranilate, pyridine, 0–5 °C, 4 h, r...

Jump to Scheme 8

Album

Supp Info

Full Research Paper

Published 09 Dec 2025

Full text

Other Beilstein-Institut Open Science Activities

/ Help / Support & Contact / E-Alerts / Privacy Policy / Terms & Conditions / Impressum