2 article(s) from Conlon, Patrick F
Examples of equipment used to perform mechanochemistry on nucleoside and nucleotide substrates (not...
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Nucleoside tritylation effected by hand grinding in a heated mortar and pestle.
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Persilylation of ribonucleoside hydroxy groups (and in situ acylation of cytidine) in a MBM.
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Nucleoside amine and carboxylic acid Boc protection using an improvised attritor-type mill.
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Nucleobase Boc protection via transient silylation using an improvised attritor-type mill.
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Chemoselective N-acylation of an aminonucleoside using LAG in a MBM.
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Azide–alkyne cycloaddition reactions performed in a copper vessel in a MBM.
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a) Custom-machined copper vessel and zirconia balls used to perform CuAAC reactions (showing: upper...
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Thiolate displacement reactions of nucleoside derivatives in a MBM.
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Selenocyanate displacement reactions of nucleoside derivatives in a MBM.
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Nucleobase glycosidation reactions and subsequent deacetylation performed in a MBM.
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Regioselective phosphorylation of nicotinamide riboside in a MBM.
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Preparation of nucleoside phosphoramidites in a MBM using ionic liquid-stabilised chlorophosphorami...
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Preparation of a nucleoside phosphite triester using LAG in a MBM.
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Internucleoside phosphate coupling linkages in a MBM.
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Preparation of ADPR analogues using in a MBM.
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Synthesis of pyrophosphorothiolate-linked dinucleoside cap analogues in a MBM to effect hydrolytic ...
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Early low temperature mechanised ball mill as described by Mudd et al. – adapted from reference .
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Co-crystal grinding of alkylated nucleobases in an amalgam mill (N.B. no frequency was recorded in ...
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Materials used to prepare a smectic phase.
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Structures of 5-fluorouracil (5FU) and nucleoside analogue prodrugs subject to mechanochemical co-c...
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Preparation of DNA-SWNT complex in a MBM.
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Beilstein J. Org. Chem. 2018, 14, 955–970, doi:10.3762/bjoc.14.81
Model reactions of 5′-chloro-5′-deoxyadenosine (1a) with 4-methoxybenzylthiolate salts used to opti...
Thiolate displacement reactions of 5′-derivatised nucleosides using VBM.
Selenocyanate displacement reactions of 5′-derivatised nucleosides using liquid-assisted grinding (...
Beilstein J. Org. Chem. 2017, 13, 87–92, doi:10.3762/bjoc.13.11
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