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1 article(s) from Conthagamage, Udyogi N K

Effect of a photoswitchable rotaxane on membrane permeabilization across lipid compositions

Udyogi N. K. Conthagamage,
Lilia Lopez,
Zuliah A. Abdulsalam and
Víctor García-López

Beilstein J. Org. Chem. 2025, 21, 2498–2512, doi:10.3762/bjoc.21.192

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Graphical Abstract

Figure 1: a) Structural components of the rotaxanes (PEG, polyethylene glycol chain; BAA (benzylalkylammonium...

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Figure 2: Photoisomerization of rotaxane 1.

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Figure 3: Reversible photoswitching of rotaxane 1 in LUVs with varying lipid compositions. Left column: UV–vi...

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Figure 4: Summary of sulforhodamine B release from LUVs of varying lipid compositions. a) Dye release after 7...

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Figure 5: Percentage of sulforhodamine B released from EYPC/Chol 8:2 LUVs upon five irradiation cycles after ...

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Figure 6: Percentage of sulforhodamine B released from LUVs containing rotaxane 1 upon five alternating light...

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Figure 7: Evaluation of effect of axle 3 upon light exposure. a) Percentage of sulforhodamine B released from...

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Figure 8: a) Illustration of rotaxane 4 in its preferred orientation within a lipid bilayer; percentage of su...

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Published 11 Nov 2025

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