1 article(s) from Fittolani, Giulio
Overview of the methods available for the synthesis of polysaccharides. For each method, advantages...
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Overview of the classes of polysaccharides discussed in this review. Each section deals with polysa...
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Enzymatic and chemical polymerization approaches provide cellulose oligomers with a non-uniform dis...
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AGA of a collection of cellulose analogues obtained using BBs 6–9. Specifically placed modification...
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Chemical structure of the different branches G, X, L, F commonly found in XGs. Names are given foll...
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AGA of XG analogues with defined side chains. The AGA cycle includes coupling (TMSOTf), Fmoc deprot...
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Synthetic strategies and issues associated to the formation of the β(1–3) linkage.
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Convergent synthesis of β(1–3)-glucans using a regioselective glycosylation strategy.
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DMF-mediated 1,2-cis glycosylation. A) General mechanism and B) examples of α-glucans prepared usin...
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Synergistic glycosylation strategy employing a nucleophilic modulation strategy (TMSI and Ph3PO) in...
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Different approaches to produce xylans. A) Polymerization techniques including ROP, and B) enzymati...
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A) Synthesis of arabinofuranosyl-decorated xylan oligosaccharides using AGA. Representative compoun...
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Chemoenzymatic synthesis of COS utilizing a lysozyme-catalyzed transglycosylation reaction followed...
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Synthesis of COS using an orthogonal glycosylation strategy based on the use of two different LGs.
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Orthogonal N-PGs permitted the synthesis of COS with different PA.
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AGA of well-defined COS with different PA using two orthogonally protected BBs. The AGA cycle inclu...
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A) AGA of β(1–6)-N-acetylglucosamine hexasaccharide and dodecasaccharide. AGA includes cycles of co...
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‘Double-faced’ chemistry exemplified for ᴅ-Man and ʟ-Rha. Constructing β-Man linkages is considerab...
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Implementation of a capping step after each glycosylation cycle for the AGA of a 50mer oligomannosi...
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AGA enabled the synthesis of a linear α(1–6)-mannoside 100mer 93 within 188 h and with an average s...
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The 151mer branched polymannoside was synthesized by a [30 + 30 + 30 + 30 + 31] fragment coupling. ...
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PG stereocontrol strategy to obtain β-mannosides. A) The mechanism of the β-mannosylation reaction ...
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A) Mechanism of 1,2-cis stereoselective glycosylation using ManA donors. Once the ManA donor is act...
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A) The preferred 4H3 conformation of the gulosyl oxocarbenium ion favors the attack of the alcohol ...
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AGA of type I rhamnans up to 16mer using disaccharide BB 115 and CNPiv PG. The AGA cycle includes c...
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Key BBs for the synthesis of the O-antigen of Bacteroides vulgatus up to a 128mer (A) and the CPS o...
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Examples of type I and type II galactans synthesized to date.
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A) The DTBS PG stabilizes the 3H4 conformation of the Gal oxocarbenium ion favoring the attack of t...
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Homogalacturonan oligosaccharides synthesized to date. Access to different patterns of methyl-ester...
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GlfT2 from Mycobacterium tuberculosis catalyzes the sequential addition of UPD-Galf donor to a grow...
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The poor reactivity of acceptor 137 hindered a stepwise synthesis of the linear galactan backbone a...
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AGA of a linear β(1–5) and β(1–6)-linked galactan 20mer. The AGA cycle includes coupling (NIS/TfOH)...
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The 92mer arabinogalactan was synthesized using a [31 + 31 + 30] fragment coupling between a 31mer ...
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Synthesis of the branched arabinofuranose fragment using a six component one-pot synthesis. i) TTBP...
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A) Chemical structure and SNFG of the representative disaccharide units forming the GAG backbones, ...
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Synthetic challenges associated to the H/HS synthesis.
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Degradation of natural heparin and heparosan generated valuable disaccharides 150 and 151 that can ...
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A) The one-step conversion of cyanohydrin 156 to ʟ-iduronamide 157 represent the key step for the s...
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A) Chemoenzymatic synthesis of heparin structures, using different types of UDP activated natural a...
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Synthesis of the longest synthetic CS chain 181 (24mer) using donor 179 and acceptor 180 in an iter...
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AGA of a collection of HA with different lengths. The AGA cycle includes coupling (TfOH) and Lev de...
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Beilstein J. Org. Chem. 2021, 17, 1981–2025, doi:10.3762/bjoc.17.129
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