1 article(s) from Ha-Duong, Tap
Graphical Abstract
Figure 1: A) Natural threonine and its trifluoromethyl analogues sawhorse projections. B) Structure of Boc-pr...
Scheme 1: Synthesis of (2S,3R)-Boc-CF3-Thr(Bzl) 9.
Scheme 2: Synthesis of (2S,3S)-Boc-CF3-Thr 14.
Scheme 3: Synthesis of pentapeptides 1a–4a and 1b–4b.
Figure 2: Probability distribution of the peptide conformations as a function of end-to-end distance (defined...
Figure 3: Probability distribution of the peptide dihedral angles ψ for the three central residues Val2 (blac...
Figure 4: Effects of compounds 1–4 on Aβ1-42 fibrillization assessed by ThT-fluorescence spectroscopy at 10:1...