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Beilstein J. Org. Chem. 2026, 22, 443–450, doi:10.3762/bjoc.22.31
Graphical Abstract
Figure 1: The structure of the highly bioactive trans-(+)-taxifolin.
Scheme 1: The currently most widely applied synthetic method for trans-(±)-taxifolin and its derivatives (a) ...
Scheme 2: Darzens reaction of 2 with various arylaldehydes under the optimized conditions. Reaction condition...
Scheme 3: Synthesis of trans-(±)-taxifolin and its derivatives via the approach developed in this work. Yield...
Beilstein J. Org. Chem. 2024, 20, 1468–1475, doi:10.3762/bjoc.20.130
Scheme 1: Synthesis of aniline derivatives from 2-cyclohexenones or derivatives thereof.
Scheme 2: Synthesis of (E)-2-arylidene-3-cyclohexenones 2.
Scheme 3: Substrate scope of (E)-2-arylidene-3-cyclohexenones 2. Conditions: reactions were conducted with 2a...
Scheme 4: Substrate scope of primary amines 3. Conditions: reactions conducted with 2 (0.2 mmol) and 3b–y (2....
Scheme 5: Gram-scale reaction and successive one-pot synthesis.
Scheme 6: Synthetic manipulation.