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Beilstein J. Org. Chem. 2026, 22, 1229–1236, doi:10.3762/bjoc.22.99
Graphical Abstract
Scheme 1: Schematic representation of the synthesis of AKBA-Ala. I) SOCl2, toluene, 20 °C, 18 h. II) ʟ-Alanin...
Figure 1: Stacked 1H NMR spectra of all products (AKBA and AKBA-Cl: 300 MHz; AKBA-Ala-t-Bu and AKBA-Ala: 400 ...
Figure 2: Displacement ellipsoid plot and atom-numbering scheme of AKBA (drawn at 30% probability; one of two...
Figure 3: Displacement ellipsoid plot and atom-numbering scheme of AKBA-Ala (drawn at 50% probability). Hydro...
Figure 4: Inhibition of 5-LOX product formation by AKBA and AKBA-Ala in human neutrophils. Neutrophils were p...
Figure 5: Induction of pro-resolving 15-LOX products and RvD5 by AKBA and AKBA-Ala in human M2-MDMs. M2-MDM (...