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Beilstein J. Org. Chem. 2025, 21, 2211–2219, doi:10.3762/bjoc.21.168
Graphical Abstract
Scheme 1: Coupling reaction of 1 and chiral primary and secondary amines. The central biphenyl moiety rotates...
Figure 1: CD and UV spectra of (a) tertiary amines (S)-2a–e and (b) quaternary ammonium salts (S)-2f,g and (R...
Figure 2: Schematic representation of the preferred conformation of (S)-2a.
Figure 3: Four major conformers of (S)-3a based on B3LYP/6-31G* level.
Figure 4: Four major conformers of (S)-3f based on B3LYP/6-31G* level.
Figure 5: The distribution of conformers of (S)-3a–h against dihedral angles ϕ (C6–C1–C1'–C6') calculated by ...
Figure 6: Crystal structure of (S)-2b. Four conformers exist in the unit cell. Hydrogen atoms are omitted for...
Figure 7: The relationship between the ACD values and excess of P conformer. Excess of P conformer (%) = ([P]...