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2 article(s) from Mohr, Kathrin I

Lanyamycin, a macrolide antibiotic from Sorangium cellulosum, strain Soce 481 (Myxobacteria)

Lucky S. Mulwa,
Rolf Jansen,
Dimas F. Praditya,
Kathrin I. Mohr,
Patrick W. Okanya,
Joachim Wink,
Eike Steinmann and
Marc Stadler

Beilstein J. Org. Chem. 2018, 14, 1554–1562, doi:10.3762/bjoc.14.132

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Graphical Abstract

Figure 1: Lanyamycin (1/2), differing at C-26, isolated from Sorangium cellulosum (Soce 481).

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Figure 2: Structure fragments of lanyamycin (1/2) from ¹H,¹H-COSY spectrum (bold bonds) and selected ¹H,¹³C-H...

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Figure 3: Structure of bafilomycin A₁.

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Figure 4: 3D Model of the macrolactone ring of lanyamycin (1/2) and selected ROESY correlations. Green arrows...

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Figure 5: HCV assay: NC = negative control, EGCG = positive control, Cpd1 = lanyamycin (1/2).

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Published 26 Jun 2018

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Volatiles from the tropical ascomycete Daldinia clavata (Hypoxylaceae, Xylariales)

Tao Wang,
Kathrin I. Mohr,
Marc Stadler and
Jeroen S. Dickschat

Beilstein J. Org. Chem. 2018, 14, 135–147, doi:10.3762/bjoc.14.9

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Scheme 1: A selection of widespread fungal volatiles.

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Figure 1: Total ion chromatogram of a representative headspace extract from Daldinia clavata MUCL 47436. Peak...

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Scheme 2: Identified volatiles from Daldinia clavata MUCL 47436.

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Figure 2: Mass spectra of volatiles from D. clavata that were identified by synthesis.

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Scheme 3: Synthesis of manicone (10).

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Scheme 4: Synthesis of a racemic mixture of all four diastereomers of 11.

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Figure 3: Gas chromatographic analysis of 11 on a homochiral stationary phase. a) Synthetic mixture of all ei...

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Scheme 5: Enantioselective synthesis of (4R,5S,6S)-11c and (4S,5R,6S)-11d.

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Scheme 6: Epimerisations of (4R,5S,6S)-11c and (4S,5R,6S)-11d under basic conditions.

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Figure 4: Gas chromatographic analysis of 11 on a homochiral stationary phase. a) Synthetic mixture of all ei...

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Scheme 7: Proposed biosynthesis for (4R,5R,6S)-11a.

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Figure 5: Mass spectra of a) 6-methyl-5,6-dihydro-2H-pyran-2-one (9), b) 6-propyl-5,6-dihydro-2H-pyran-2-one,...

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Scheme 8: Synthesis of 6-methyl-5,6-dihydro-2H-pyran-2-one (9) and 6-nonyl-2H-pyran-2-one (17).

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Published 12 Jan 2018

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