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Beilstein J. Org. Chem. 2026, 22, 882–887, doi:10.3762/bjoc.22.68
Graphical Abstract
Scheme 1: Synthesis and reactivity of α-boryl lithium species.
Scheme 2: Diastereodivergent electrophilic trapping of α-boryl lithium derivatives.
Figure 1: Cyclopropylmethyl iodide starting materials.
Scheme 3: Reactivity of α-boryl lithium intermediates 5 possessing alkyl substituents at the allylic position....
Scheme 4: Effect of the nature of the substituent R3 on the diastereoselectivity.
Scheme 5: Mechanistic hypothesis to rationalize the diastereoselectivity.