Inclusion of the insecticide fenitrothion in dimethylated-β-cyclodextrin: unusual guest disorder in the solid state and efficient retardation of the hydrolysis rate of the complexed guest in alkaline solution

Dyanne L. Cruickshank,
Natalia M. Rougier,
Raquel V. Vico,
Susan A. Bourne,
Elba I. Buján,
Mino R. Caira and
Rita H. de Rossi

Full Research Paper
Published 17 Jan 2013

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1. Graphical Abstract
2. Figure 1: Chemical structure of fenitrothion (1).
  
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3. Figure 2: Representative TGA (top) and DSC (bottom) traces for DIMEB·1.
  
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4. Figure 3: The asymmetric unit in DIMEB•1 viewed along [010] (top) and [100] (bottom). H atoms are omitted for...
  
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5. Figure 4: The host molecules in the asymmetric unit of DIMEB·1 with the labelling of both residues and atoms ...
  
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6. Figure 5: The rotamers of 1 occupying the cavity of host molecule A. Common atoms have labels with suffix A, ...
  
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7. Figure 6: Stereoview of the three disordered guest components that occupy the cavity of host molecule B. Gues...
  
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8. Figure 7: Space-filling diagrams showing the relative orientations of guest molecules within the cavities of ...
  
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9. Figure 8: Packing diagrams of the DIMEB·1 structure, viewed along [100] (left) and [010] (right). The symmetr...
  
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10. Figure 9: Induced circular dichroism (a) and UV–vis (b) spectra of 1 in the presence of β-CD (10 mM, green), ...
  
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11. Scheme 1: Reaction of fenitrothion in basic media.
  
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12. Figure 10: Plot of k_obs versus [DIMEB] for the hydrolysis reaction of fenitrothion with HO^– at different conce...
  
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13. Scheme 2: Mechanism of the hydrolysis reaction of 1 mediated by DIMEB.
  
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