1 article(s) from Ryan, Christopher A
Structure of DNA and PNA.
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PNA binding modes: (A) PNA–dsDNA 1:1 triplex; (B) PNA–DNA–PNA strand-invasion triplex; (C) the Hoog...
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Structure of P-form PNA–DNA–PNA triplex from reference . (A) view in the major groove and (B) view ...
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Structures of backbone-modified PNA.
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Structures of PNA having α- and γ-substituted backbones.
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Structures of modified nucleobases in PNA to improve Hoogsteen hydrogen bonding to guanine and aden...
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Proposed hydrogen bonding schemes for modified PNA nucleobases designed to recognize pyrimidines or...
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Modified nucleobases to modulate Watson–Crick base pairing and chemically reactive crosslinking PNA...
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Examples of triplets formed by Janus-wedge PNA nucleobases (blue). R1 denotes DNA, RNA, or PNA back...
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Examples of fluorescent PNA nucleobases. R1 denotes DNA, RNA, or PNA backbones.
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Endosomal entrapment and escape pathways of PNA and PNA conjugates.
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(A) representative cell-penetrating peptides (CPPs), (B) conjugation designs and linker chemistries....
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Proposed delivery mode by pHLIP-PNA conjugates (A) the transmembrane section of pHLIP interacting w...
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Structures of modified penetratin CPP conjugates with PNA linked through either disulfide (for stud...
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Chemical structure of C9–PNA, a stable amphipathic (cyclic-peptide)–PNA conjugate.
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Structures of PNA conjugates with a lipophilic triphenylphosphonium cation (TPP–PNA) through (A) th...
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Structures of (A) chloesteryl–PNA, (B) cholate–PNA and (C) cholate–PNA(cholate)3.
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Structures of PNA–GalNAc conjugates (A) (GalNAc)2K, (B) triantennary (GalNAc)3, and (C) trivalent (...
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Vitamin B12–PNA conjugates with different linkages.
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Structures of (A) neomycin B, (B) PNA–neamine conjugate, and (C) PNA–neosamine conjugate.
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PNA clamp (red) binding to target DNA containing a mixture of sequences (A) PNA binds with higher a...
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Rolling circle amplification using PNA openers (red) to invade a dsDNA target forming a P-loop. A p...
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Molecular beacons containing generic fluorophores (Fl) and quenchers (Q) recognizing a complementar...
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(A) Light-up fluorophores such as thiazole orange display fluorescence enhancement upon binding to ...
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Templated fluorogenic detection of oligonucleotides using two PNAs. (A) Templated FRET depends on h...
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Lateral flow devices use a streptavidin labeled strip on nitrocellulose paper to anchor a capture P...
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Beilstein J. Org. Chem. 2021, 17, 1641–1688, doi:10.3762/bjoc.17.116
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