1 article(s) from Vasseur, Jean-Jacques
Demasking under reducing agents of ON prodrugs modified as phosphotriesters with A) benzyl groups  ...
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A) Synthesis via phosphoramidite chemistry and B) demasking under the reducing environment of 2’-O-...
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Synthesis via phosphoramidite chemistry of various 2’-O-alkyldithiomethyl (RSSM)-modified RNAs bear...
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A) siRNA conjugates to cholesterol  and B) PNA conjugates to a triphenylphosphonium  through a disu...
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Synthesis via phosphoramidite chemistry and deprotection mediated by nitroreductase/NADH of hypoxia...
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Synthesis via phosphoramidite chemistry and conversion mediated by nitroreductase/NADH of hypoxia-a...
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Incorporation of O6-(4-nitrobenzyl)-2’-deoxyguanosine into an ON prone to form a G-quadruplex struc...
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Synthesis and mechanism for the demasking of ON prodrugs from A) S-acylthioethyl phosphotriester  a...
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Oligothymidylates bearing A) 2,2-bis(ethoxycarbonyl)-3-(pivaloyloxy)propyl- and B) 2-cyano-2(2-phen...
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Oligothymidylates containing esterase and thermo-labile (4-acetylthio-2,2-dimethyl-3-oxobutyl) phos...
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Phosphoramidites and the corresponding RNA prodrugs protected as A) t-Bu-SATE, B) OH-SATE and C) A-...
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Mechanism of the hydrolysis of 2’-O-acyloxymethyl ONs mediated by carboxyesterases . The hydrolysis...
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Synthesis of partially 2’-O-PivOM-modified RNAs  and 2’-O-PiBuOM-modified RNAs  using their corresp...
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A) 2’-O-amino and guanidino-containing acetal ester phosphoramidites and B) 2’-O-(amino acid) aceta...
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Prodrugs of tricyclo-ONs functionalized with A) ethyl (tcee-T) and B) hexadecyl (tchd-T) ester func...
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Demasking mechanism of fma thiophosphate triesters in CpG ODN upon heat action .
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Thermolytic cleavage of the hydroxy-alkylated thiophosphate and phosphato-/thiophosphato-alkylated ...
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Synthesis via phosphoramidite chemistry and thermolytic cleavage of alkylated (diisopropyl, diethyl...
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Synthesis of thermosensitive prodrugs of ODNs containing fma thiophosphate triesters combined to po...
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Caging of deoxycytidine in methylphosphonate ONs by using the thermolabile phenylsulfonylcarbamoyl ...
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Biotinylated 1-(5-(aminomethyl)-2-nitrophenyl)ethyl phosphoramidite used to cage the 5’-end of a si...
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Introduction and cleavage of 1-(4,5-dimethoxy-2-nitrophenyl)ethyl (DMNPE)  and cyclododecyl-DMNPE (...
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Post-synthetic introduction of a thioether-enol phosphodiester (TEEP) linkage into a DNAzyme by the...
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A) NPP dT and dG phosphoramidites [91,92] and B) NPOM U and G phosphoramidites  used to introduce photocag...
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Introduction of the photocaged 3-NPOM nucleobase into phosphorothioate antisense and morpholino ant...
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Control of the activity of an antisense ODN using a photocaged hairpin . Formation of the hairpin s...
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Control of alternative splicing using phosphorothioate (PS) 2’-OMe-photocaged ONs resulting from th...
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A) Light activation of a photocaged DNAzyme incorporating 3-NPOM thymidine in its catalytic site ; ...
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Incorporation of 3-(6-nitropiperonyloxymethyl) (NPOM) thymidine and 4-nitropiperonylethyl (NPE) deo...
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Synthesis of a photocaged DNA decoy from a 3-NPOM thymidine phosphoramidite and release of the NPOM...
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Synthesis of a caged DNA decoy hairpin containing a 7-nitroindole nucleotide and release of the mod...
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Caged-2’-adenosines used by MacMillan et al [93,94] (X = O) and Piccirilli et al  (X = S) to study RNA mec...
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Synthesis of circular ODNs containing a photolabile linker as described by Tang et al. [101,104].
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Control of RNA digestion with RNase H using light activation of a photocaged hairpin .
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Photocontrol of RNA degradation using caged circular antisense ODNs containing a photoresponsive li...
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Control of RNA translation using an “RNA bandage” consisting of two short 2’-OMe ONs linked togethe...
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Control of alternative splicing using photocaged ONs resulting from the incorporation of an o-nitro...
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A) Light deactivation of a photocaged DNAzyme incorporating one photocleavable spacer in its cataly...
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Solid-phase synthesis of a caged vit E-siRNA conjugate and its release upon UV irradiation .
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Synthesis of a siRNA conjugated to a nanoparticle (NP) via a cyclooctene heterolinker from a siRNA-...
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Beilstein J. Org. Chem. 2018, 14, 436–469, doi:10.3762/bjoc.14.32
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