3 article(s) from Zhang, Lei
Graphical Abstract
Figure 1: A) Structure of the pioneering azobenzene-modified DNA [16] compared with the photoswitchable PNA struc...
Scheme 1: Solid-phase synthesis of photoswitchable PNAs; Aeg = N-(2-aminoethyl)glycine, Bhoc = benzhydryloxyc...
Figure 2: Time-dependent conversion to the thermodynamically stable isomer of PNA12(oF4Azo) (3; green triangl...
Figure 3: A) Melting curves of a 1 µM duplex solution in phosphate buffer (10 mM NaH2PO4, 150 mM NaCl, pH 7.4...
Figure 4: Outline of the displacement assay principle, in which a photoswitchable PNA probe (blue) hybridizes...
Figure 5: Time-dependent fluorescence signals from two independent experiments at 520 nm of 0.75 μM FAM/BHQ-d...
Graphical Abstract
Figure 1: Representative examples of bioactive tetracyclic compounds containing the indole motif.
Scheme 1: Synthetic route for indolo[1,2-a]quinazoline derivatives by a sequential Ullmann-type C–C and C–N c...
Graphical Abstract
Figure 1: Representative biologically relevant examples of 5,6-dihydroindolo[1,2-a]quinoxaline derivatives.
Scheme 1: Reagents and conditions: (a) CF3COOH, anhydrous dichloromethane, reflux; (b) NaBH4, MeOH.