Asymmetric reactions in continuous flow

• Xiao Yin Mak,
• Paola Laurino and
• Peter H. Seeberger

Beilstein J. Org. Chem. 2009, 5, No. 19, doi:10.3762/bjoc.5.19

• advantage of a continuous flow system, the resolution of a mixture of the racemic acetyl-amino acid (DL-58) was carried out in tandem with a microextractor for the selective separation of the resulting chiral products (Scheme 17). The racemic substrate was introduced into the microreactor in a buffered