Beilstein J. Org. Chem.2009,5, No. 19, doi:10.3762/bjoc.5.19
as donor, and subsequently to a Mannichreaction with α-iminoglyoxylate.
Supported and heterogeneous catalysis
Chiral catalysts and ligands are often expensive and the complete separation of these components from reaction products can frequently be quite challenging. Degradation products and leaching
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Graphical Abstract
Scheme 1:
Enantioselective addition of trimethylsilyl cyanide to benzaldehyde.