The oxanorbornene approach to 3-hydroxy, 3,4-dihydroxy and 3,4,5-trihydroxy derivatives of 2-aminocyclohexanecarboxylic acid

• Ishmael B. Masesane,
• Andrei S. Batsanov,
• Judith A. K. Howard,
• Raju Mondal and
• Patrick G. Steel

Beilstein J. Org. Chem. 2006, 2, No. 9, doi:10.1186/1860-5397-2-9

• selectivity leading to exclusive formation of 12. In a similar fashion, and in agreement with the idea of two directing groups working in concert, epoxidation of the exo derived diene 5 afforded exclusive formation of epoxide 13. Speculating that disruption of any directing effects through the use of more