Beilstein J. Org. Chem.2006,2, No. 3, doi:10.1186/1860-5397-2-3
claim that this procedure for preparing primary amides starting from arylhalides is better than another procedure which uses hexamethyldisilazane (HMDS). [26] Therefore, the EcoScale for the latter procedure was also calculated to compare the two preparations.
The sum of all penalty points is 68 (Table
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Graphical Abstract
Scheme 1:
Reduction of nitrobenzene to aniline [23]