Easy, efficient and versatile one-pot synthesis of Janus-type-substituted fullerenols

• Marius Kunkel and
• Sebastian Polarz

Beilstein J. Org. Chem. 2019, 15, 901–905, doi:10.3762/bjoc.15.87

• . These fullerenol amphiphiles can serve as suitable precursors for further reactions resulting in new applications for fullerenols. Keywords: amphiphile; C60Cl6; fullerene; fullerenol; one-pot; Introduction The roman god Janus, who is typically depicted with two faces, metaphorically stands for duality

• synthetic pathways, which allow to introduce a broader variety of substituents and better yield. We report an easy and efficient one-pot approach using C60Cl6 as a precursor. The attachment of substituents, in our case primary amines, and the polyhydroxylation of the fullerene core are performed

• simultaneously by using a common phase transfer reaction which enables even the combination of water-soluble substituents with the precursor C60Cl6. High yields of Janus-fullerenol derivatives bearing five defined substituents on one pole of the C60 core combined with in average 19 (+/−3) oxygen containing