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Search for "Cope rearrangement" in Full Text gives 29 result(s) in Beilstein Journal of Organic Chemistry.

Gold(I)-catalyzed enantioselective cycloaddition reactions

  • Fernando López and
  • José L. Mascareñas

Beilstein J. Org. Chem. 2013, 9, 2250–2264, doi:10.3762/bjoc.9.264

Graphical Abstract
  • -catalyzed Cope rearrangement through a boat-like transition state would deliver the cis-2,3-disubstituted cycloheptenyl acetates of type 5 (Scheme 3) [43]. Although the process was essentially developed in a racemic fashion, by using Au3/AgSbF6 or a combination of Au4 and (PhO)3PAuSbF6 (Scheme 3), the
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Published 30 Oct 2013

The chemistry of bisallenes

  • Henning Hopf and
  • Georgios Markopoulos

Beilstein J. Org. Chem. 2012, 8, 1936–1998, doi:10.3762/bjoc.8.225

Graphical Abstract
  • double oxy-Cope rearrangement), and the resulting 76 subsequently undergoes an electrocylic ring closure to a four-membered ring system. On workup (hydrolysis) a mixture of the cis and trans isomers of 77 is obtained in very good yield (ca. 80%). A conjugated bisallene carrying three diphenylphosphine
  • precursors [112]. A radical cation Cope rearrangement of 1,5-hexadiyne (129) to the 1,2,4,5-hexatetraene radical cation was initiated by oxidizing bipropargyl radiolytically in a Freon matrix at 77 K [113]. The 129→2→130 sequence, and in particular its last step, has also been used several times for the
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Published 15 Nov 2012

An enantiomerically pure siderophore type ligand for the diastereoselective 1 : 1 complexation of lanthanide(III) ions

  • Markus Albrecht,
  • Olga Osetska,
  • Thomas Abel,
  • Gebhard Haberhauer and
  • Eva Ziegler

Beilstein J. Org. Chem. 2009, 5, No. 78, doi:10.3762/bjoc.5.78

Graphical Abstract
  • peptidic scaffold and the final ligand 1a-H3 is obtained in good yield (90%). Successive Cope rearrangement of the spacers to the 5-position of the quinoline moiety is not observed under the chosen reaction conditions. 1H NMR spectra of 4 and 1a-H3 show pronounced differences for the resonances of the 8
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Published 11 Dec 2009

Sordarin, an antifungal agent with a unique mode of action

  • Huan Liang

Beilstein J. Org. Chem. 2008, 4, No. 31, doi:10.3762/bjoc.4.31

Graphical Abstract
  • Cope rearrangement and an intramolecular Diels-Alder reaction. The substrate for the Cope rearrangement was prepared by the merger of two cyclopentene units (Scheme 1). First, the addition of chloro compound 8 [18] to aldehyde 9 [19] occurred smoothly using the CrCl3/LAH system, developed by Hiyama et
  • al. [20]. The resultant alcohol was converted to the methyl ether using NaH and MeI. The subsequent Cope rearrangement of 10 occurred at 200 °C via a boat-like transition state [18] to yield 11. The elaboration of this material to 12 involved treatment with singlet oxygen and AcCl [21] to yield α,β
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Published 05 Sep 2008
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