Terpenoids from Glechoma hederacea var. longituba and their biological activities

• Dong Hyun Kim,
• Song Lim Ham,
• Zahra Khan,
• Sun Yeou Kim,
• Sang Un Choi,
• Chung Sub Kim and
• Kang Ro Lee

Beilstein J. Org. Chem. 2022, 18, 555–566, doi:10.3762/bjoc.18.58

• ) cell line. Keywords: antineuroinflammation; cytotoxicity; Glechoma hederacea var. longituba; neurotrophic effect; terpenoid; Introduction Glechoma hederacea var. longituba is a perennial plant in the family Labiatae. It is commonly known as ‘ground ivy’ and ‘gill over the ground’ and is widely

• University #191, Hambakmeoro, Yeonsu-gu, Incheon 21936, Republic of Korea Gachon Institute of Pharmaceutical Science, Gachon University, Incheon 21936, Republic of Korea Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea 10.3762/bjoc.18.58 Abstract Glechoma hederacea var

• . longituba (common name: ground ivy) has been used for the treatment of asthma, bronchitis, cholelithiasis, colds, and inflammation. In the present study, three new sesquiterpene glycosides (1–3), two new diterpene glycosides (4 and 5), and four known compounds (6–9) were isolated from its MeOH extract. A