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Search for "Huisgen cycloaddition" in Full Text gives 26 result(s) in Beilstein Journal of Organic Chemistry.

Synthesis of 2-substituted 9-oxa-guanines {5-aminooxazolo[5,4-d]pyrimidin- 7(6H)-ones} and 9-oxa-2-thio- xanthines {5-mercaptooxazolo[5,4-d]pyrimidin- 7(6H)-ones}

  • Subrata Mandal,
  • Wen Tai Li,
  • Yan Bai,
  • Jon D. Robertus and
  • Sean M. Kerwin

Beilstein J. Org. Chem. 2008, 4, No. 26, doi:10.3762/bjoc.4.26

Graphical Abstract
  • with benzyl azide or 2-morpholinoethyl azide in the presence of catalytic CuSO4 and sodium ascorbate to afford the triazoles 9 and 10, respectively, in good yield (Figure 5). The copper-catalyzed Huisgen cycloaddition of terminal alkynes and alkyl azides favors formation of the 1,4-triazole
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Published 25 Jul 2008
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