Cyclodextrins tethered with oligolactides – green synthesis and structural assessment

• Cristian Peptu,
• Mihaela Balan-Porcarasu,
• Alena Šišková,
• Ľudovít Škultéty and
• Jaroslav Mosnáček

Beilstein J. Org. Chem. 2017, 13, 779–792, doi:10.3762/bjoc.13.77

• and the catalyst. The synthetic procedure in which CDs and L-lactide (L-LA) are reacting in bulk at relatively high temperature of 110 °C was investigated considering the structural composition of the products. The obtained products were thoroughly characterized via mass spectrometry methods with soft

• chromatography; L-lactide; MALDI; mass spectrometry; NMR; Introduction Cyclodextrin derivatives are increasingly important and their variety is dictated by the wide range of applications in which these compounds are employed with preponderance in the pharmaceutical field [1][2]. The employed strategies for the

• polylactides have been prepared using different catalytic systems with good results in synthesis of star polymers with relatively high molecular weight and low polydispersity, by the “core first” method. Polymerization of L-lactide was performed by anionic ROP initiated by potassium alkoxides of α-CD partially

Methylenelactide: vinyl polymerization and spatial reactivity effects

• Judita Britner and
• Helmut Ritter

Beilstein J. Org. Chem. 2016, 12, 2378–2389, doi:10.3762/bjoc.12.232

• donating (“pushing”) oxygen atom. Monomers with such substitution patterns are defined as captodative or push–pull monomers [1]. MLA was first synthesized in 1969 by Scheibelhoffer et al. through a bromination of L-lactide followed by a basic HBr elimination [2]. In 2008, the first Diels–Alder reaction

• recently investigated [8]. Up to now, it was not possible to polymerize MLA via ring opening [9]. Only indirectly, unsaturated polylactide carrying vinyl side groups can be obtained through a copolymerization of chlorolactide with L-lactide followed by subsequent dehydrochlorination [10]. Recently, thiol