Beilstein J. Org. Chem.2013,9, 2422–2433, doi:10.3762/bjoc.9.280
: asymmetric catalysis; DFT; 1,3-dipolar cycloaddition; gold catalysis; NICS; NTR; oxazolones; prolines; Introduction
The synthesis of α-amino acids employing an α-amino carbonyl template constitutes the most straightforward route to introduce the α-side chain [1]. As a valid example, oxazol-5-(4H)-ones