Nonanebis(peroxoic acid): a stable peracid for oxidative bromination of aminoanthracene-9,10-dione

• Vilas Venunath Patil and
• Ganapati Subray Shankarling

Beilstein J. Org. Chem. 2014, 10, 921–928, doi:10.3762/bjoc.10.90

• protocol has a broad scope for the bromination of various substituted and unsubstituted aminoanthracene-9,10-diones. Keywords: aminoanthracene-9,10-dione; benzanthrone; KBr; nonanebis(peroxoic acid); oxidative bromination; Introduction The brominated aminoanthracene-9,10-dione derivatives and

• aminoanthracene-9,10-dione deactivate the ring towards electrophilic substitution [11]. Generally, the bromination of aminoanthracene-9,10-dione is carried out in sulfuric acid [12][13][14][15] (20 to 98%) and nitrobenzene [16][17] at a high temperature (80 to 120 °C) with or without a catalyst (like Cu or CuSO4

• ) [18][19][20][21]. In all processes, hazardous molecular bromine is used as a bromine source [11][12][13][14][15][16][17][18][19][20][21]. Ghaieni et. al. [22][23] have reported bromination of aminoanthracene-9,10-dione in a mixture of conc sulfuric acid with chlorobenzene, glacial acetic acid