Beilstein J. Org. Chem.2018,14, 1120–1180, doi:10.3762/bjoc.14.98
, Erzurum, Turkey 10.3762/bjoc.14.98 Abstract This review focuses on the chemistry of benzo-annulated tropones and tropolones reported since the beginning of the 20th century, which are currently used as tools by the synthetic and biological communities.
Keywords: benzotropolone; benzotropone
oxidation of black tea and have been found to have numerous biological activities such as antipathogenic and anticancer activity, and they prevent heart disease, hypertension, and diabetes (Figure 1) [39][43]. Because of the pharmacological relevance of benzotropone analogues, the development of new and
occurring tropones and tropolones [9]. In addition to this, chemistry of dibenzosuberenone, which is one of the dibenzotropone isomers, has already reviewed by us [45].
There are three possible benzotropone isomers: 4,5-benzotropone (11), 2,3-benzotropone (12), and 3,4-benzotropone (13, Figure 2). The
PDF
Graphical Abstract
Scheme 1:
Tropone (1), tropolone (2) and their resonance structures.