Beilstein J. Org. Chem.2018,14, 2236–2241, doi:10.3762/bjoc.14.198
= (2.29 ± 0.27) × 106 M−1) is 3.9 times larger than that of P (Ka = (5.87 ± 0.24) × 105 M−1).
Keywords: berberine; biphenarenes; host–guest complexes; molecular recognition; palmatine; Introduction
Host–guest chemistry in water is significantly important due to its extensive applications in biology
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Graphical Abstract
Scheme 1:
Synthesis of 2,2’-CBP4 and the chemical structures of P and B.