An air-stable bisboron complex: a practical bidentate Lewis acid catalyst

• Longcheng Hong,
• Sebastian Ahles,
• Andreas H. Heindl,
• Gastelle Tiétcha,
• Andrey Petrov,
• Zhenpin Lu,
• Christian Logemann and
• Hermann A. Wegner

Beilstein J. Org. Chem. 2018, 14, 618–625, doi:10.3762/bjoc.14.48

• Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom Institute of Inorganic Chemistry, University of Cologne, Greinstr. 4, 50939 Cologne, Germany 10.3762/bjoc.14.48 Abstract We report an air-stable bisboron complex as an efficient catalyst for the inverse electron-demand Diels–Alder (IEDDA

• enhancing its practicality. Comparative reactions were carried out to evaluate its catalytic activity in IEDDA reactions of diazine including phthalazine as well as 1,2,4,5-tetrazine. Keywords: air-stable catalyst; bidentate; bisboron; diazine; Diels–Alder; Lewis acid; Introduction The development of

• LUMOs are rather high in energy [9][10][11][12]. In the past years, we demonstrated a bisboron bidentate Lewis acid (Scheme 1, A) as an efficient catalyst for the IEDDA reaction of 1,2-diazines to access 1,2-substituted aromatics [13][14]. Additionally, we could incorporate this reactivity in domino