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Search for "bolaamphiphiles" in Full Text gives 3 result(s) in Beilstein Journal of Organic Chemistry.

Aggregation behaviour of a single-chain, phenylene-modified bolalipid and its miscibility with classical phospholipids

  • Simon Drescher,
  • Vasil M. Garamus,
  • Christopher J. Garvey,
  • Annette Meister and
  • Alfred Blume

Beilstein J. Org. Chem. 2017, 13, 995–1007, doi:10.3762/bjoc.13.99

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  • -C18pPhC18-PC is partially miscible with saturated phosphatidylcholines; however, closed lipid vesicles with an increased thermal stability were not found. Instead, bilayer fragments and disk-like aggregates are formed. Keywords: aggregation behaviour; bolaamphiphiles; bolalipids; membrane lipids; mixing
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Published 23 May 2017

Planar-bilayer activities of linear oligoester bolaamphiphiles

  • Jonathan K. W. Chui,
  • Thomas M. Fyles and
  • Horace Luong

Beilstein J. Org. Chem. 2011, 7, 1562–1569, doi:10.3762/bjoc.7.184

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  • Jonathan K. W. Chui Thomas M. Fyles Horace Luong Department of Chemistry, University of Victoria, Victoria BC, Canada 10.3762/bjoc.7.184 Abstract Voltage-clamp experiments of eight oligoester bolaamphiphiles in two subclasses are described. Syntheses of three new terephthalate-based compounds
  • sets of unabridged records? And are there phenomena that are beyond the scope of this representation? To provide a suitably focused yet sufficiently diverse suite of molecules in order to answer these questions, two classes of bolaamphiphiles were selected (Scheme 1). Both the phthalate and solid-phase
  • between different linear bolaamphiphiles and correspond to the influence of each unique architecture on the overall system behavior. This is experimental support for the proposal [10] that there is some underlying energetic landscape that is as much a property of the system (lipid, water, and compound) as
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Published 22 Nov 2011

Symmetrical and unsymmetrical α,ω-nucleobase amide-conjugated systems

  • Sławomir Boncel,
  • Maciej Mączka,
  • Krzysztof K. K. Koziol,
  • Radosław Motyka and
  • Krzysztof Z. Walczak

Beilstein J. Org. Chem. 2010, 6, No. 34, doi:10.3762/bjoc.6.34

Graphical Abstract
  • ,ω-nucleobase bolaamphiphiles (VII), capable of forming extraordinary nanotopologies [6]. In order to synthesise a new group of modified, mainly pyrimidinic nucleosides, we employed a simple and effective synthetic pathway based on the catalytic aminolysis of carboxylic acids. Our synthetic approach
  • the two model compounds 11 and 12. The supramolecular behaviour of conjugated nucleobase-based bolaamphiphiles was examined by TEM. A JEOL 200 FX, operating at 200 kV, was used to obtain the typical images as shown in Figure 4. For the microscopic studies, saturated ethanolic solutions of 11 and 12
  • prepared by ultrasonication were subjected to slow vaporisation at −20 °C. Microcrystalline assemblies were grown directly on copper grids for TEM analyses. This procedure of growth accompanied by careful investigations revealed that thymine- (A, B) and 5-nitrouracil-based (C) bolaamphiphiles derived from
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Preliminary Communication
Published 12 Apr 2010
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