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Search for "bolalipids" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.

Aggregation behaviour of a single-chain, phenylene-modified bolalipid and its miscibility with classical phospholipids

  • Simon Drescher,
  • Vasil M. Garamus,
  • Christopher J. Garvey,
  • Annette Meister and
  • Alfred Blume

Beilstein J. Org. Chem. 2017, 13, 995–1007, doi:10.3762/bjoc.13.99

Graphical Abstract
  • -C18pPhC18-PC is partially miscible with saturated phosphatidylcholines; however, closed lipid vesicles with an increased thermal stability were not found. Instead, bilayer fragments and disk-like aggregates are formed. Keywords: aggregation behaviour; bolaamphiphiles; bolalipids; membrane lipids; mixing
  • behaviour; nanofibres; self-assembly; Introduction Bolalipids are amphiphilic molecules consisting of two hydrophilic headgroups attached to both ends of a long hydrocarbon spacer [1]. The hydrophobic spacer is composed of either a single alkyl chain or two chains connected via a glycerol moiety. These
  • bolalipids originate in membranes of some species of archaea, e.g., thermoacidophiles and these archaeal membranes can withstand extreme living conditions, such as high temperatures or low pH values [2][3][4]. Archaea are quite different from bacteria and eukaryotes [5][6][7][8][9], which is also reflected
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Published 23 May 2017
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