Beilstein J. Org. Chem.2011,7, 555–564, doi:10.3762/bjoc.7.64
NHC–Au(I) complex (S)-6a was consequently investigated as the catalyst in the asymmetric intramolecular hydroamination of allenes. This reaction has been achieved with high enantioselectivity by a chiralphosphine–Au(I) complex [87][88][89][90][91][92][93]. Treatment of allene 11 with (S)-6a and
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Graphical Abstract
Figure 1:
Monodentate NHCs with sterically hindered N-substituents.