Beilstein J. Org. Chem.2021,17, 2922–2923, doi:10.3762/bjoc.17.200
supramolecular chemistry for the assembly of polymer fibers and the synthesis of well-defined polysaccharides. In the direction of materials, cryogels and reinforced hydrogels are discussed, as well as 3D-printed poly(caprolactone) biomaterials. In addition, properties of thermoresponsive materials and self
Beilstein J. Org. Chem.2021,17, 2553–2569, doi:10.3762/bjoc.17.171
Luke O. Jones Leah Williams Tasmin Boam Martin Kalmet Chidubem Oguike Fiona L. Hatton Department of Materials, Loughborough University, Loughborough, LE11 3TU, UK 10.3762/bjoc.17.171 Abstract Cryogels are macroporous polymeric structures formed from the cryogelation of monomers/polymers in a
highlights the fundamentals of macroporous cryogel preparation, cryogel properties that can be useful in the highlighted biomedical applications, followed by a comprehensive review of recent studies in these areas. Research evaluated includes the use of cryogels to combat various types of cancer, for
implantation without surgical incision, and use as highly effective wound dressings. Furthermore, conclusions and outlooks are discussed for the use of these promising and durable macroporous cryogels.
Keywords: 3D-bioprinting; cryogels; drug delivery; injectable cryogel; macroporous hydrogel; wound healing
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Graphical Abstract
Figure 1:
Schematic representation of the process of aqueous cryogel formation, using (a) monomers/small mole...