Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids

• M. Isabel Burguete,
• Eduardo García-Verdugo and
• Santiago V. Luis

Beilstein J. Org. Chem. 2011, 7, 1347–1359, doi:10.3762/bjoc.7.159

• enantioselective reactions. In the examples shown, the activity, selectivity and enantioselectivity of the processes was modulated through the proper adjustment of the reaction parameters, such as pressure, temperature, flow, and the nature of the scF, etc., allowing for a rapid optimization of the process. An

Asymmetric reactions in continuous flow

• Xiao Yin Mak,
• Paola Laurino and
• Peter H. Seeberger

Beilstein J. Org. Chem. 2009, 5, No. 19, doi:10.3762/bjoc.5.19

• conditions and in the case of heterogeneous catalysis, potential long term use of the catalysts. This review will highlight some of the continuous flow asymmetric reactions described to date. Review Homogeneous catalysis Only a few examples of homogeneous enantioselective reactions in continuous flow have

The first salen- type ligands derived from 3',5'-diamino- 3',5'-dideoxythymidine and -dideoxyxylothymidine and their corresponding copper(II) complexes

• Daniel Koth,
• Michael Gottschaldt,
• Helmar Görls and
• Karolin Pohle

Beilstein J. Org. Chem. 2006, 2, No. 17, doi:10.1186/1860-5397-2-17

• as the replacement of the thymine base by different functional groups or the immobilization of the complexes by the nucleobase enables the resulting complexes to become promising candidates as catalysts for enantioselective reactions. Conclusion In summary, an effective route for the synthesis of 3