Beilstein J. Org. Chem.2017,13, 1008–1021, doi:10.3762/bjoc.13.100
: gold nanoparticles; glyco nanoparticles; glyconanomaterials; immunology; targeting; Introduction
Carbohydrates are well recognized as crucial biomolecules for their capability to produce an enormous number of biocodes which are translated into their ability to promote or suppress a plethora of
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Graphical Abstract
Figure 1:
Schematic overview on the glyco-gold nanoparticles synthetic approaches.
Beilstein J. Org. Chem.2014,10, 1339–1346, doi:10.3762/bjoc.10.136
-HIV abacavir and lamivudine ester prodrug candidates is described. The effects of multimerization of the HIV drug derivatives on biocompatible and water-dispersible glyconanomaterials have been tested. The drugs were released from the glyconanoparticles in acidic conditions and were able to inhibit
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Graphical Abstract
Figure 1:
The prepared lamivudine (3TC) and abacavir (ABC) potential prodrugs and the corresponding 3TC- and ...