Beilstein J. Org. Chem.2008,4, No. 47, doi:10.3762/bjoc.4.47
% yield. Hydrolysis and reduction of the major diastereoisomeric product of the reaction yields atropisomeric biaryls in >99:1 enantiomeric ratios.
Keywords: atropisomer; biaryl; dynamic resolution; ephedrine; imdazolidine; oxazolidine; Introduction
Atropisomeric biaryl compounds have proved to be among