Beilstein J. Org. Chem.2020,16, 778–790, doi:10.3762/bjoc.16.71
advantages of this protocol.
Keywords: C–C-bond formation; C3-funtionalization of indole; diindolylmethane; Friedel–Crafts reaction; indole; indole-3-carbinol; large-scale synthesis; recyclability; Introduction
(1H-Indol-3-yl)methanols have emerged as versatile pre-electrophiles for C–C functionalization
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Graphical Abstract
Figure 1:
Structures of trifluoromethylated compounds and their biological activities.