Elucidating the glycan-binding specificity and structure of Cucumis melo agglutinin, a new R-type lectin

• Jon Lundstrøm,
• Emilie Gillon,
• Valérie Chazalet,
• Nicole Kerekes,
• Antonio Di Maio,
• Ten Feizi,
• Yan Liu,
• Annabelle Varrot and
• Daniel Bojar

Beilstein J. Org. Chem. 2024, 20, 306–320, doi:10.3762/bjoc.20.31

• garnered attention for their roles as laboratory probes and potential therapeutics. Here, we report the discovery and characterization of Cucumis melo agglutinin (CMA1), a new R-type lectin from melon. Our findings reveal CMA1’s unique glycan-binding profile, mechanistically explained by its 3D structure

• groundwork for further exploration of its biological and therapeutic potential. Keywords: carbohydrate; glycan array; melon; plant lectin; R-type; Introduction Lectins have long been the subject of intense scientific scrutiny, serving as molecular bridges that span the realms of biochemistry, cellular

• , there are still significant gaps in our understanding. Further, in general, few melon lectins have been studied in detail. Some reports indicate the presence of chitooligosaccharide-binding (i.e., β1-4 GlcNAc oligomers) lectins from phloem exudates of melons [16][17], as well as R-type lectins in bitter

A fluorescent probe for detection of Hg²⁺ ions constructed by tetramethyl cucurbit[6]uril and 1,2-bis(4-pyridyl)ethene

• Xiaoqian Chen,
• Naqin Yang,
• Yue Ma,
• Xinan Yang and
• Peihua Ma

Beilstein J. Org. Chem. 2023, 19, 864–872, doi:10.3762/bjoc.19.63

• became a free G molecule with proton peaks Ha, Hb. This indicates that Hg2+ ions may coordinate with the port of TMeQ[6] to form a 1:1 coordination compound, which has a competitive effect with the G molecule. The G molecule wrapped in the cavity of the melon ring is squeezed out, and the proton peak of

Synthesis of odorants in flow and their applications in perfumery

• Merlin Kleoff,
• Paul Kiler and
• Philipp Heretsch

Beilstein J. Org. Chem. 2022, 18, 754–768, doi:10.3762/bjoc.18.76

• , alcohol 24, which is a homolog of geraniol, has a strong fruity, melon-like odor profile [35]. Green odorants To the family of green odorants belong those having a scent that is reminiscent of leaves and grasses, but also odorants that are minty, camphorous, or resinous. Peppermint is a fresh, cold, and

Heterogeneous photocatalysis in flow chemical reactors

• Christopher G. Thomson,
• Ai-Lan Lee and
• Filipe Vilela

Beilstein J. Org. Chem. 2020, 16, 1495–1549, doi:10.3762/bjoc.16.125

• , first reported in 1834 by Liebig, which he named “melon” [119]. The material consists of two-dimensional sheets of hexatopic, hexagonal sp2-hybridised carbon and nitrogen atoms, linked by bridging tertiary amines (Figure 9) [120]. The material is crystalline as sheets are held together by strong π