Beilstein J. Org. Chem.2019,15, 2092–2104, doi:10.3762/bjoc.15.207
Fisciano (Salerno), Italy 10.3762/bjoc.15.207 Abstract The synthesis of the triple-calix[6]arene derivative 6 in which three calix[6]arene macrocycles are linked to a central 1,3,5-trimethylbenzene moiety is reported. Derivative 6 is able to give multiple-threading processes in the presence of
stereoselective formation of endo-alkyl pseudo[n]rotaxane stereoisomers.
Keywords: calixarene; multiple-threading; pseudo[n]rotaxane; stereoisomers; Introduction
The self-assembly [1] of smaller components to larger aggregates represents one of the most spectacular phenomena in supramolecular chemistry [2][3][4
directed towards the study of multiple-threading processes of host systems bearing multiple-wheels (multivalent hosts). On this basis, interesting handcuff-like interpenetrated systems (Figure 1) have been reported to date in literature [10][11][12][13][14][15][16], which represent non-trivial
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Graphical Abstract
Figure 1:
Sketch of the currently known prototypical examples of handcuff-derived architectures.