Beilstein J. Org. Chem.2012,8, 621–628, doi:10.3762/bjoc.8.69
feasible.
Keywords: isothiazole; nitrochlorobutadiene; nitropyrazole; nucleophilic substitution; pyrimidine; small rings; Introduction
Nitropolychlorobutadienes are potent precursors for a variety of highly functionalized acyclic and (hetero)cyclic compounds. The readily accessible 2-nitroperchloro-1,3
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Graphical Abstract
Figure 1:
Promising starting materials for biologically active compounds.