Beilstein J. Org. Chem.2012,8, 514–521, doi:10.3762/bjoc.8.58
scarcely characterised.
Keywords: glycosidases inhibitors; iminosugars; nojirimycins; pyrrolidines; trehalases; Introduction
Trehalase (EC3.2.1.28) is a glycosidase that catalyses trehalose (α-D-glucopyranosyl-α-D-glucopyranoside 1, Figure 1) [1][2][3] hydrolysis. It was found initially at the end of the
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Graphical Abstract
Figure 1:
Structure of trehalose (1), validoxylamine A (2), 1-thiatrehazolin (3), trehalostatin (4), casuarin...