Beilstein J. Org. Chem.2015,11, 773–783, doi:10.3762/bjoc.11.87
; growth factor; integrin; osteodifferentiation; stem cells; Review
Introduction
Current bone grafting therapeutics do not provide satisfying solutions to the problems of non-healing bone defects. The gold-standard therapy is the grafting of autologous bone; however, it is limited by low availability as
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Graphical Abstract
Figure 1:
Differentiation potential of mesenchymal stem cells (MSCs) in bone marrow. MSCs can differentiate i...