Search results

Search for "pesticides" in Full Text gives 38 result(s) in Beilstein Journal of Organic Chemistry.

Trifluoromethylated hydrazones and acylhydrazones as potent nitrogen-containing fluorinated building blocks

  • Zhang Dongxu

Beilstein J. Org. Chem. 2023, 19, 1741–1754, doi:10.3762/bjoc.19.127

Graphical Abstract
  • lipophilicity and metabolic stability compared to nonfluorinated compounds [1][2][3][4][5]. At present, about 300 drug molecules and over 400 pesticides on the market contain at least one fluorine atom [6][7]. Therefore, the development of novel and effective synthetic methodologies for the synthesis of
  • group has attracted a significant level of attention, and many trifluoromethylated pyrazoles have been used in medicinal products or in pesticides [66]. The [3 + 2] cycloaddition reactions are considered among the most powerful tools for the synthesis of versatile fluoroalkylated pyrazoles. Enol ethers
PDF
Album
Review
Published 15 Nov 2023

Non-noble metal-catalyzed cross-dehydrogenation coupling (CDC) involving ether α-C(sp3)–H to construct C–C bonds

  • Hui Yu and
  • Feng Xu

Beilstein J. Org. Chem. 2023, 19, 1259–1288, doi:10.3762/bjoc.19.94

Graphical Abstract
  • products [25][26][27][28][29][30][31]. Ether motifs can significantly modify the pharmacological properties of parent molecules, including increasing lipophilicity and affecting half-life, which play a crucial role in biology, pharmaceuticals, and pesticides [32][33]. Some examples of ether-containing
PDF
Album
Review
Published 06 Sep 2023

Discrimination of β-cyclodextrin/hazelnut (Corylus avellana L.) oil/flavonoid glycoside and flavonolignan ternary complexes by Fourier-transform infrared spectroscopy coupled with principal component analysis

  • Nicoleta G. Hădărugă,
  • Gabriela Popescu,
  • Dina Gligor (Pane),
  • Cristina L. Mitroi,
  • Sorin M. Stanciu and
  • Daniel Ioan Hădărugă

Beilstein J. Org. Chem. 2023, 19, 380–398, doi:10.3762/bjoc.19.30

Graphical Abstract
  • biologically active molecules on CD-coated polymers used in chromatography [62]. PCA was used for the evaluation of the similarity/dissimilarity of some pesticides, especially fungicides and herbicides, using the effect of a water-soluble β-CD polymer on the apparent pesticide’s lipophilicity [63]. Also
PDF
Album
Supp Info
Full Research Paper
Published 28 Mar 2023

Total synthesis of insect sex pheromones: recent improvements based on iron-mediated cross-coupling chemistry

  • Eric Gayon,
  • Guillaume Lefèvre,
  • Olivier Guerret,
  • Adrien Tintar and
  • Pablo Chourreu

Beilstein J. Org. Chem. 2023, 19, 158–166, doi:10.3762/bjoc.19.15

Graphical Abstract
  • insect sex pheromones as an alternative to conventional pesticides is in constant growth. In this report, we discuss the recent contributions brought by our groups in the field of iron-catalyzed cross-couplings applied to the synthesis of insect pheromones. The pivotal question of the development of
  • environmental problems, particularly pollution and soil persistence, led in recent years to a decrease in the use of so-called conventional protection products for the protection of crops and plants. Some of these synthetic pesticides, such dimethoate (pesticides for the protection of cherry crops) or
  • chlordecone (pesticides for the protection of banana crops) [1], have recently been forbidden in the EU. In this context, the development of eco-friendlier solutions for the protection of crops and plants is a major challenge. This is why biocontrol (that is: all plant protection methods that use natural
PDF
Album
Perspective
Published 14 Feb 2023

An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates

  • Timur O. Zanakhov,
  • Ekaterina E. Galenko,
  • Mikhail S. Novikov and
  • Alexander F. Khlebnikov

Beilstein J. Org. Chem. 2022, 18, 738–745, doi:10.3762/bjoc.18.74

Graphical Abstract
  • -triaryl-substituted and 1,2,5,6-tetrasubstituted nicotinates. Keywords: isoxazole; methyl nicotinate; molybdenum hexacarbonyl; 4-pyridone; ring expansion; Introduction Pyridine moieties are present in many natural products, drugs, pesticides and industrial materials. Pyridine fragments are used in drugs
PDF
Album
Supp Info
Full Research Paper
Published 23 Jun 2022

19F NMR as a tool in chemical biology

  • Diana Gimenez,
  • Aoife Phelan,
  • Cormac D. Murphy and
  • Steven L. Cobb

Beilstein J. Org. Chem. 2021, 17, 293–318, doi:10.3762/bjoc.17.28

Graphical Abstract
  • important element in the broader space of chemical biology [2]. Many commercial and industrial compounds are fluorinated, including refrigerants, degreasers, drugs, pesticides and anti-stick materials, and consequently there is a high degree of interaction between fluorinated compounds and nature [3
PDF
Album
Review
Published 28 Jan 2021

An overview on disulfide-catalyzed and -cocatalyzed photoreactions

  • Yeersen Patehebieke

Beilstein J. Org. Chem. 2020, 16, 1418–1435, doi:10.3762/bjoc.16.118

Graphical Abstract
  • ; photocatalysis; thiyl radical; Introduction Organic disulfides are often used as the skeleton for drugs, pesticides, rubber auxiliaries, polymers, and electronic materials [1]. Over the past decade, organic disulfide-involving photoreactions have attracted increasing attention. Disulfides have versatile
PDF
Album
Review
Published 23 Jun 2020

A novel three-component reaction between isocyanides, alcohols or thiols and elemental sulfur: a mild, catalyst-free approach towards O-thiocarbamates and dithiocarbamates

  • András György Németh,
  • György Miklós Keserű and
  • Péter Ábrányi-Balogh

Beilstein J. Org. Chem. 2019, 15, 1523–1533, doi:10.3762/bjoc.15.155

Graphical Abstract
  • used as H2S donors in biological systems [18] and as intermediates in pharmaceutically significant organic syntheses [19][20]. The dithiocarbamate structural moiety can be found in biologically active molecules widely applied as fungicides, herbicides, pesticides [21][22][23][24][25] and in some cases
PDF
Album
Supp Info
Full Research Paper
Published 10 Jul 2019

One-pot three-component route for the synthesis of S-trifluoromethyl dithiocarbamates using Togni’s reagent

  • Azim Ziyaei Halimehjani,
  • Martin Dračínský and
  • Petr Beier

Beilstein J. Org. Chem. 2017, 13, 2502–2508, doi:10.3762/bjoc.13.247

Graphical Abstract
  • rotation are in reasonable agreement with the experiments. Keywords: dithiocarbamates; electrophilic trifluoromethylation; Togni reagents; Introduction Dithiocarbamates are well known for their manifold applications as pesticides, fungicides and crop protection agents in agriculture [1][2][3], as
PDF
Album
Supp Info
Letter
Published 24 Nov 2017

Pd(OAc)2/Ph3P-catalyzed dimerization of isoprene and synthesis of monoterpenic heterocycles

  • Dominik Kellner,
  • Maximilian Weger,
  • Andrea Gini and
  • Olga García Mancheño

Beilstein J. Org. Chem. 2017, 13, 1807–1815, doi:10.3762/bjoc.13.175

Graphical Abstract
  • applications such as pesticides, odors or flavors (Scheme 1, reaction 3). Results and Discussion Dimerization of isoprene We focused our study on the use of commercially available palladium catalysts and inexpensive Ph3P as catalytic system under practical non-anhydrous and atmospheric or low-pressure
PDF
Album
Supp Info
Full Research Paper
Published 29 Aug 2017

An efficient Pd–NHC catalyst system in situ generated from Na2PdCl4 and PEG-functionalized imidazolium salts for Mizoroki–Heck reactions in water

  • Nan Sun,
  • Meng Chen,
  • Liqun Jin,
  • Wei Zhao,
  • Baoxiang Hu,
  • Zhenlu Shen and
  • Xinquan Hu

Beilstein J. Org. Chem. 2017, 13, 1735–1744, doi:10.3762/bjoc.13.168

Graphical Abstract
  • NMR spectra. Acknowledgements This work was supported by the National Natural Science Foundations of China (21473160). We also thank for the support from “Zhejiang Key Course of Chemical Engineering and Technology” and “Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology of
PDF
Album
Supp Info
Full Research Paper
Published 21 Aug 2017

Cycloheximide congeners produced by Streptomyces sp. SC0581 and photoinduced interconversion between (E)- and (Z)-2,3-dehydroanhydrocycloheximides

  • Li Yang,
  • Ping Wu,
  • Jinghua Xue,
  • Huitong Tan,
  • Zheng Zhang and
  • Xiaoyi Wei

Beilstein J. Org. Chem. 2017, 13, 1039–1049, doi:10.3762/bjoc.13.103

Graphical Abstract
  • without the toxic side-effects could provide a viable lead of therapeutic drugs or agricultural pesticides. During the course of our searching for bioactive microbial metabolites [8][9], a culture extract of Streptomyces sp. SC0581 was found to show antifungal activity against the phytopathogen
PDF
Album
Supp Info
Full Research Paper
Published 30 May 2017

Synthesis and enzymatic ketonization of the 5-(halo)-2-hydroxymuconates and 5-(halo)-2-hydroxy-2,4-pentadienoates

  • Tyler M. M. Stack,
  • William H. Johnson Jr. and
  • Christian P. Whitman

Beilstein J. Org. Chem. 2017, 13, 1022–1031, doi:10.3762/bjoc.13.101

Graphical Abstract
  • environmental contaminants [1][2][3][4][5]. Halogenated aromatic compounds are found in many industrial commodities such as pesticides, flame-retardants, hydraulic fluids, and synthetic intermediates for pharmaceutical agents [2][3][4]. Several strategies are being explored to remove these toxic compounds from
PDF
Album
Supp Info
Full Research Paper
Published 26 May 2017

Total synthesis of TMG-chitotriomycin based on an automated electrochemical assembly of a disaccharide building block

  • Yuta Isoda,
  • Norihiko Sasaki,
  • Kei Kitamura,
  • Shuji Takahashi,
  • Sujit Manmode,
  • Naoko Takeda-Okuda,
  • Jun-ichi Tamura,
  • Toshiki Nokami and
  • Toshiyuki Itoh

Beilstein J. Org. Chem. 2017, 13, 919–924, doi:10.3762/bjoc.13.93

Graphical Abstract
  • synthesis was completed by Yu [8][9]. Although the activity of TMG-chitotriomycin (1) was moderate, it selectively inhibits glucosaminidases derived from insects and fungi. Therefore, TMG-chitotriomycin (1) has a potential as a lead compound for safe insecticides and pesticides. Recently, the total
PDF
Album
Supp Info
Full Research Paper
Published 16 May 2017

N-Propargylamines: versatile building blocks in the construction of thiazole cores

  • S. Arshadi,
  • E. Vessally,
  • L. Edjlali,
  • R. Hosseinzadeh-Khanmiri and
  • E. Ghorbani-Kalhor

Beilstein J. Org. Chem. 2017, 13, 625–638, doi:10.3762/bjoc.13.61

Graphical Abstract
  • kinase activity [10][11][12][13][14] (Figure 1). This compound class is also a crucial part of many natural products such as vitamin B1 (thiamine), epothilone, dolastatin, and many more (Figure 2) [15][16][17][18][19][20][21][22][23][24]. Moreover, thiazoles are widely applied as pesticides and dyes [25
PDF
Album
Review
Published 30 Mar 2017

Transition-metal-catalyzed synthesis of phenols and aryl thiols

  • Yajun Liu,
  • Shasha Liu and
  • Yan Xiao

Beilstein J. Org. Chem. 2017, 13, 589–611, doi:10.3762/bjoc.13.58

Graphical Abstract
  • synthesis and also final products, playing important roles in pharmaceutical molecules, pesticides and polymers in both academia and industry [1][2][3][4]. Some classic drugs which employ phenols or aryl thiols as central structural motifs are shown in Figure 1. In the past decade, the transition-metal
PDF
Album
Review
Published 23 Mar 2017

Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis

  • Flavio Fanelli,
  • Giovanna Parisi,
  • Leonardo Degennaro and
  • Renzo Luisi

Beilstein J. Org. Chem. 2017, 13, 520–542, doi:10.3762/bjoc.13.51

Graphical Abstract
  • reported a metal-free photocatalytic aerobic oxidation of thiols to disulfides under continuous-flow conditions [64]. Disulfides are useful molecules employed as drugs, anti-oxidants or pesticides as well as rubber vulcanizating agents [65]. Symmetric disulfides are generally obtained by oxidative coupling
PDF
Album
Review
Published 14 Mar 2017

Structure–efficiency relationships of cyclodextrin scavengers in the hydrolytic degradation of organophosphorus compounds

  • Sophie Letort,
  • Michaël Bosco,
  • Benedetta Cornelio,
  • Frédérique Brégier,
  • Sébastien Daulon,
  • Géraldine Gouhier and
  • François Estour

Beilstein J. Org. Chem. 2017, 13, 417–427, doi:10.3762/bjoc.13.45

Graphical Abstract
  • of the agents. The degradation efficiency was found to be dependent on the relative position of the heterocycle towards the reactive group as well as on the nature of the organophosphorus derivative. Keywords: cyclodextrin; decontamination; enzyme mimic; nerve agents; organophosphorus pesticides
  • ; Introduction Originally employed as pesticides, organophosphorus compounds were further developed as chemical warfare agents during the Second World War. These compounds act as potent irreversible inhibitors of cholinesterases [1][2][3][4][5][6] and are able to cause lethal intoxications [3]. Despite the
  • measures adopted to reduce the risk of accidental poisoning by pesticides [7][8][9][10][11] and the Chemical Weapons Convention aiming at the non-proliferation of chemical weapons or their precursors, organophosphorus compounds still constitute a threat to civilian and military people. Moreover, due to the
PDF
Album
Supp Info
Full Research Paper
Published 06 Mar 2017

Stabilization of nanosized titanium dioxide by cyclodextrin polymers and its photocatalytic effect on the degradation of wastewater pollutants

  • Tamás Zoltán Agócs,
  • István Puskás,
  • Erzsébet Varga,
  • Mónika Molnár and
  • Éva Fenyvesi

Beilstein J. Org. Chem. 2016, 12, 2873–2882, doi:10.3762/bjoc.12.286

Graphical Abstract
  • treatment procedure(s) are elaborated for the removal of such microcontaminants. Various sorbents containing cyclodextrin (CD) have been developed aiming at the removal of pharmaceutical residues, pesticides and other endocrine disrupting compounds from purified wastewater [6][7]. CDs are cyclic
  • .) and microcontaminants occurring in water (pharmaceutical and cosmetic active agents, pesticides, etc.). The CD derivatives, which are well soluble in water, such as hydroxypropyl and methylated CDs, can enhance desorption of the contaminants from the soil and are useful in soil remediation
  • bisphenol A was enhanced in aqueous solutions containing β-CD [25], while the photodecomposition of pesticides of similar structure (parathion and paraoxon) was inhibited or catalyzed, respectively, by β-CD [26]. The complex formation can either protect the drug from the effect of light or accelerate the
PDF
Album
Full Research Paper
Published 28 Dec 2016

Mutagenic activity of quaternary ammonium salt derivatives of carbohydrates

  • Barbara Dmochowska,
  • Karol Sikora,
  • Anna Woziwodzka,
  • Jacek Piosik and
  • Beata Podgórska

Beilstein J. Org. Chem. 2016, 12, 1434–1439, doi:10.3762/bjoc.12.138

Graphical Abstract
  • construction [7][8][9]. Moreover, QASs are applied in industry, agriculture (as pesticides and herbicides) [10], and chemistry (as catalysts and solvents) [11][12]. QASs are also used as ingredients in hair conditioners, shampoos, and toothpastes [13]. Ionic liquids (IL) are recognized as a particularly
PDF
Album
Supp Info
Full Research Paper
Published 12 Jul 2016

Natural products from microbes associated with insects

  • Christine Beemelmanns,
  • Huijuan Guo,
  • Maja Rischer and
  • Michael Poulsen

Beilstein J. Org. Chem. 2016, 12, 314–327, doi:10.3762/bjoc.12.34

Graphical Abstract
  • Beauveria bassiana and Metarhizium anisopliae, have a broad host range encompassing over 1,000 insect species from more than 50 different insect families. These fungi are used as biocontrol agents for invertebrate pest control, a commercial alternative to chemical pesticides [125][126][127]. Other
PDF
Album
Review
Published 19 Feb 2016

Interactions of cyclodextrins and their derivatives with toxic organophosphorus compounds

  • Sophie Letort,
  • Sébastien Balieu,
  • William Erb,
  • Géraldine Gouhier and
  • François Estour

Beilstein J. Org. Chem. 2016, 12, 204–228, doi:10.3762/bjoc.12.23

Graphical Abstract
  • on the current use of cyclodextrins against organophosphorus compound intoxications. Organophosphorus pesticides and nerve agents play a determinant role in the inhibition of cholinesterases. The cyclic structure of cyclodextrins and their toroidal shape are perfectly suitable to design new chemical
  • scavengers able to trap and hydrolyze the organophosphorus compounds before they reach their biological target. Keywords: cyclodextrin; enzyme mimic; nerve agents; organophosphorus compounds; pesticides; Introduction Due to their biological activities, organophosphorus compounds have had considerable
  • against the pests or in the military. While the administration of organophosphorus drugs is carefully controlled, improper use of pesticides and chemical warfare agents, the so called “nerve agents”, can cause fatal poisonings through cholinesterase inhibition in tissues and brain [20]. Neurotoxic
PDF
Album
Review
Published 05 Feb 2016

A convenient four-component one-pot strategy toward the synthesis of pyrazolo[3,4-d]pyrimidines

  • Mingxing Liu,
  • Jiarong Li,
  • Hongxin Chai,
  • Kai Zhang,
  • Deli Yang,
  • Qi Zhang and
  • Daxin Shi

Beilstein J. Org. Chem. 2015, 11, 2125–2131, doi:10.3762/bjoc.11.229

Graphical Abstract
  • important because of their biological activity [1][2][3][4][5][6]. They have shown a wide range of pharmacological potential such as kinase inhibitors [1], antitumor [7][8], anti-inflammatory [9][10], antimicrobial [11][12][13], pesticides [14], radio protectant [15] and cardiovascular activity [16][17
PDF
Album
Supp Info
Full Research Paper
Published 06 Nov 2015

Electrochemical selenium- and iodonium-initiated cyclisation of hydroxy-functionalised 1,4-dienes

  • Philipp Röse,
  • Steffen Emge,
  • Jun-ichi Yoshida and
  • Gerhard Hilt

Beilstein J. Org. Chem. 2015, 11, 174–183, doi:10.3762/bjoc.11.18

Graphical Abstract
  • are in turn potential substrates for the synthesis of functionalised heterocycles. Particularly, we were interested in the synthesis of tetrahydrofuran and pyran derivatives. Those heterocycles are prevalent substructures in many natural compounds, pesticides and drugs with antifungal and
PDF
Album
Supp Info
Full Research Paper
Published 28 Jan 2015

Removal of volatile organic compounds using amphiphilic cyclodextrin-coated polypropylene

  • Ludmilla Lumholdt,
  • Sophie Fourmentin,
  • Thorbjørn T. Nielsen and
  • Kim L. Larsen

Beilstein J. Org. Chem. 2014, 10, 2743–2750, doi:10.3762/bjoc.10.290

Graphical Abstract
  • in order to improve the aquatic ecosystem [1]. Later in 2008, the EU elaborated on the Water Framework Directive defining several problematic compounds, including various pesticides, endocrine disruptors, and hydrocarbons such as benzene and benzene derivatives, as compounds requiring immediate and
PDF
Album
Full Research Paper
Published 24 Nov 2014
Other Beilstein-Institut Open Science Activities