Beilstein J. Org. Chem.2019,15, 1061–1064, doi:10.3762/bjoc.15.103
propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.
Keywords: alkyne hydroamination; cyclocondensation; Lewis acid catalysis; multicomponent reactions; propargylurea; Introduction
The pioneering publications of Beller and
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Graphical Abstract
Figure 1:
Examples of imidazole (1 and 2) and oxazole (3) syntheses from propargylamides previously reported ...