Dissecting Mechanochemistry III

• Lars Borchardt and
• José G. Hernández

Beilstein J. Org. Chem. 2022, 18, 1454–1456, doi:10.3762/bjoc.18.150

• , Colombia 10.3762/bjoc.18.150 In the past ten years, the use of mechanochemical techniques (e.g., grinding, milling, extrusion, pulsed ultrasonication, resonant acoustic mixing, etc.) have widespread in the field of organic chemistry, enabling the development of new and more sustainable protocols for

Polymer and small molecule mechanochemistry: closer than ever

• José G. Hernández

Beilstein J. Org. Chem. 2022, 18, 1225–1235, doi:10.3762/bjoc.18.128

• molecule mechanochemistry sometimes overlap, evidencing the connection between both approaches. Keywords: ball milling; mechanochemistry; mechanophore; polymer; pulsed ultrasonication; Introduction In the past two decades, the growth in popularity of mechanochemistry has been unmistakable. During this

• (mechanophores) embedded along the polymer chains (Figure 1a) [1][2][3][4]. This is mostly accomplished through pulsed ultrasonication, and to a lesser extent by single-molecule force spectroscopy techniques [5][6]. The second approach habitually makes use of ball milling techniques to bring together small

• created two seemingly distinct lines of thought within the field of mechanochemistry, which kept both areas to evolve mostly separately. On the one hand, polymer mechanochemistry by pulsed ultrasonication is believed to exhibit higher control at the microscopic level, for example, by enabling the